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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
北京百奥莱博科技有限公司
- 库存:
370
- 英文名:
AX-024
- 规格:
1mL(10mM)|2mg|5mg|10mg|25mg|50mg|100mg
特别提示:包括细胞因子释放抑制剂(AX-024)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:细胞因子释放抑制剂(AX-024)
英文名称:AX-024
产品货号:M05073
产品规格:1mL(10mM)|2mg|5mg|10mg|25mg|50mg|100mg
AX-024是一种细胞因子释放抑制剂,可以有效抑制白细胞介素-6(IL-6),肿瘤坏死因子-α(TNFα),干扰素-γ(IFN-γ),IL-10和IL-17A的产生。
注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
CAS号:1370544-73-2
纯度:98.0%
分子式:C₂₁H₂₂FNO₂
分子量:339.4
结构式:
储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。
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M04041 PknG抑制剂(AX20017) 1mL(10mM)|5mg|10mg|25mg|50mg
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文献和实验-H2AX Detection in Somatic and Germ Cells of Mice
The phosphorylation of histone H2AX at serine 139 (γ-H2AX) is one of the first steps of DNA damage response and its detection is widely used as a sensitive marker for DNA double-strand breaks induced by ionizing radiation or other genotoxic
Histone H2AX Phosphorylation: A Marker for DNA Damage
) are generated that rapidly result in the phosphorylation of histone H2A variant H2AX. Because phosphorylation of H2AX at Ser 139 (γ-H2AX) is abundant, fast, and correlates well with each DSB, it is the most sensitive marker that can be used to examine the DNA
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, environmental effects, and aging, as well as in the clinic. DSBs can be detected in the nuclei of cultured cells and tissues with an antibody to H2AX phosphorylated on serine residue 139 (γ-H2AX). DSB levels can be obtained
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