- 询价
- 上海博湖
- BH-K21869
- 进口、国产
- 2025年07月12日
- WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
- 详见说明书
- 详见说明书
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- 详细信息
- 技术资料
- 抗体名：
结构蛋白家族3抗体品牌
- 抗体英文名：
Anti-TCTN3/TECT3
- 靶点：
详见说明书
- 浓度：
1mg/1ml
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
- 宿主：
详见说明书
- 供应商：
上海博湖
- 库存：
大量
- 级别：
详见说明书
- 目录编号：
详见说明书
- 抗原来源：
Rabbit
- 保质期：
详见说明书
- 适应物种：
详见说明书
- 标记物：
详见说明书
- 克隆性：
多克隆
- 保存条件：
Store at -20 °C
- 形态：
详见说明书
- 亚型：
IgG
- 免疫原：
KLH conjugated synthetic peptide derived from human TCTN3/TECT3
- 规格：
0.2ml/200μg
结构蛋白家族3抗体品牌是用于化学反应、分析化验、研究实验、教学实验、化学配方使用的纯净化学品，产品品质卓越，价格实惠，多种规格供应，售后完善。
英文名称 Anti-TCTN3/TECT3
中文名称 结构蛋白家族3抗体品牌
别 名 C10orf61; Chromosome 10 open reading frame 61; DKFZP564D116; TCTN3; TECT3_HUMAN; Tectonic 3; Tectonic 3 precursor; Tectonic family member 3; Tectonic-3.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 细胞凋亡 生长因子和激素
蛋白分子量 predicted molecular weight: 64kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TCTN3/TECT3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
结构蛋白家族3抗体品牌产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Tect3 is a 607 amino acid single-pass type I membrane protein that belongs to the tectonic family and exists as four alternatively spliced isoforms. Tect3 interacts with MKS1 and may be involved in apoptosis regulation. The gene that encodes Tect3 contains approximately 31,560 bases and maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs and encoding nearly 1,200 genes, chromosome 10 makes up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, Cockayne syndrome, multiple endocrine neoplasia type 2 and porphyria. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.
Function : May be involved in apoptosis regulation.
Subunit : Part of the tectonic-like complex (also named B9 complex) (By similarity).
Subcellular Location : Membrane.
DISEASE : Defects in TCTN3 are the cause of orofaciodigital syndrome 4 (OFD4) [MIM:258860]. A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD4 patients have tongue nodules, multiple frenulae, broad flat nose, hypertelorism, and short rib polydactyly with tibial dysplasia (Majewski syndrome). The presence of severe tibial aplasia differentiates OFD4 from OFD1. Additional features of cystic dysplastic kidneys and brain malformation, including occipital encephalocele, are observed in severely affected patients.
Defects in TCTN3 are the cause of Joubert syndrome 18 (JBTS18) [MIM:614815]. A form of Joubert syndrome, a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. JBTS18 patients have vermis agenesis and the molar tooth sign as well as severe kyphoscoliosis. Other features include intrauterine growth retardation, oral anomalies, micrognathism, polydactyly and camptodactyly, joint laxity, horseshoe kidney, and ventricular septal defect. Note=TCTN3-mutated fibroblasts from JBTS18 patients fail to respond to Shh agonists suggesting that at least some of the defects in affected individuals may be secondary to reduced Shh signaling (PubMed:22883145).
Similarity : Belongs to the tectonic family.
Database links : UniProtKB/Swiss-Prot: Q6NUS6.2
结构蛋白家族3抗体品牌具有全、新、优、品、好四大特点：
全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。
新：产品更新速度较快，基本上每周都有新产品出现。
优：产品质量好，投诉比较少。
好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务，可根据您科研的需求，满足您的需要，质量保证，价格合理。
一、标记流程
委托标记服务，请下载并详细填写《委托标记申请单》，待我公司标记室技术人员研究、确认后答复，并办理委托标记事宜。
二、各种标记物制备的收费标准（RMB）
我们不但提供抗体和大分子蛋白的标记服务，还提供小分子多肽及小分子蛋白的各种标记服务，提供标记化合物的服务（此化合物必须适用于标记），价格另议。
一抗和二坑的区别：
第一抗体就是平常所说的抗体，即能和抗原特异性结合。
第二抗体是能和抗体结合的，即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体，二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说，抗原进入机体刺激机体免疫系统产生免疫应答，由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团，而且一抗可以至少结合两种其他基团（底物和二抗）。
一抗：可以特异结合底物，就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗：可以和一抗结合，并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），则不需要二抗。但这样成本很高，因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记，再来检测一抗。而一抗识别底物。这样，当一抗结合到底物上，就可以通过二抗检测出来。
Anti-VCAM-1/CD106 /FITC 荧光素标记血管内皮细胞粘附分子抗体IgGMulti-class antibodies规格： 0.2ml
CD34 CD34抗原(细胞表面的唾液粘蛋白)Multi-class antibodies规格： 0.5mg
CXCL10趋化因子10/干扰素诱导蛋白10抗体 Anti-CXCL10/IP-10 0.1ml
StAR 英文名称： 促黄体激素诱导蛋白抗体 0.2ml
Emx1 英文名称： 有脊椎动物脑发育相关蛋白Emx1抗体 0.2ml
Rhesus antibody Rh Phospho-HER2(Ty21/1222) 化HER2受体抗体 规格 0.1ml
CD34 CD34抗原(细胞表面的唾液粘蛋白)Multi-class antibodies规格： 0.5mg
SLC33A1(Acetyl-coenzyme A transportor 1) 乙酰辅酶A转运蛋白1抗原Multi-class antibodies规格： 0.5mg
Anti-BKCa channels 激活通道蛋白抗体Multi-class antibodies规格： 0.2ml
Rhesus antibody Rh PG-C/Pepsinogen 2 胃蛋白酶原C抗体 规格 0.1ml
EMA 浓缩液 0.1ml 进口分装
Tap1 英文名称： ATP结合转运因子1抗体 0.2ml
CD170 英文名称： 唾液酸结合性免疫球蛋白样凝集素5抗体 0.1ml
Anti-BKCa channels 激活通道蛋白抗体Multi-class antibodies规格： 0.2ml
Rabbit Anti-horse IgM/PE-Cy5.5 PE-Cy5.5标记的兔抗马IgM 0.1ml
FBXL20 英文名称： FBXL20蛋白抗体 0.2ml
兔抗人鸟苷三酶-发动蛋白2抗体 Anti-Dynamin 2 0.1ml
Anti-Phospho-PDGF Receptor alpha (Tyr754) /FITC 荧光素标记化血小板源性生长因子受体-α抗体IgGMulti-class antibodies规格： 0.2ml
Rhesus antibody Rh phospho-TNIK(Ser769) 化TRAF2和NCK激酶相互作用蛋白抗体 规格 0.1ml
Rabbit Anti-chi IgG/FITC 荧光素标记兔抗鸡IgGMulti-class antibodies规格： 0.3ml
Dami(人巨核细胞白血病细胞) 5×106cells/瓶×2
CCCSCK
PTPRC Others Mouse 小鼠 CD45 / PTPRC 人细胞裂解液 (阳性对照)
8910PM细胞，人卵巢癌细胞 小鼠细胞,EMT6细胞 肾小管上皮细胞Many types of cells包装：5 × 105次方(1ml)
CL-0068COS-1(非洲绿猴SV转化的肾细胞)5×106cells/瓶×2
HTEpC Pellet 人类气管上皮细胞团块 > 1 mio.cells 人骨骼肌细胞cDNAHSkMC cDNA
骨骼肌细胞培养基SkMCM
REG1A Others Cynomolgus 食蟹猴 REG1A / PSPS 人细胞裂解液 (阳性对照)
人胚胎，皮肤，肌肉;M-22
HNE2-LMP1/2细胞，人鼻咽癌细胞系 小鼠肝癌细胞,H22细胞 CM-H071人肾动脉平滑肌细胞完全培养基100mL
OS-RC-2(人肾癌细胞) 5×106cells/瓶×2
Promocell C-27101 Chondrocyte Growth Medium, 软骨细胞生长培养基(即用型) 500ml
结构蛋白家族3抗体品牌Dami(人巨核细胞白血病细胞) 5×106cells/瓶×2
CCCSCK
PTPRC Others Mouse 小鼠 CD45 / PTPRC 人细胞裂解液 (阳性对照)
8910PM细胞，人卵巢癌细胞 小鼠细胞,EMT6细胞 肾小管上皮细胞Many types of cells包装：5 × 105次方(1ml)
CL-0068COS-1(非洲绿猴SV转化的肾细胞)5×106cells/瓶×2
HTEpC Pellet 人类气管上皮细胞团块 > 1 mio.cells 人骨骼肌细胞cDNAHSkMC cDNA
英文名称 Anti-TCTN3/TECT3
中文名称 结构蛋白家族3抗体品牌
别 名 C10orf61; Chromosome 10 open reading frame 61; DKFZP564D116; TCTN3; TECT3_HUMAN; Tectonic 3; Tectonic 3 precursor; Tectonic family member 3; Tectonic-3.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 细胞凋亡 生长因子和激素
蛋白分子量 predicted molecular weight: 64kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TCTN3/TECT3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
结构蛋白家族3抗体品牌产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Tect3 is a 607 amino acid single-pass type I membrane protein that belongs to the tectonic family and exists as four alternatively spliced isoforms. Tect3 interacts with MKS1 and may be involved in apoptosis regulation. The gene that encodes Tect3 contains approximately 31,560 bases and maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs and encoding nearly 1,200 genes, chromosome 10 makes up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, Cockayne syndrome, multiple endocrine neoplasia type 2 and porphyria. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10.
Function : May be involved in apoptosis regulation.
Subunit : Part of the tectonic-like complex (also named B9 complex) (By similarity).
Subcellular Location : Membrane.
DISEASE : Defects in TCTN3 are the cause of orofaciodigital syndrome 4 (OFD4) [MIM:258860]. A form of orofaciodigital syndrome, a group of heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated phenotypic abnormalities that lead to the delineation of various subtypes. OFD4 patients have tongue nodules, multiple frenulae, broad flat nose, hypertelorism, and short rib polydactyly with tibial dysplasia (Majewski syndrome). The presence of severe tibial aplasia differentiates OFD4 from OFD1. Additional features of cystic dysplastic kidneys and brain malformation, including occipital encephalocele, are observed in severely affected patients.
Defects in TCTN3 are the cause of Joubert syndrome 18 (JBTS18) [MIM:614815]. A form of Joubert syndrome, a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. JBTS18 patients have vermis agenesis and the molar tooth sign as well as severe kyphoscoliosis. Other features include intrauterine growth retardation, oral anomalies, micrognathism, polydactyly and camptodactyly, joint laxity, horseshoe kidney, and ventricular septal defect. Note=TCTN3-mutated fibroblasts from JBTS18 patients fail to respond to Shh agonists suggesting that at least some of the defects in affected individuals may be secondary to reduced Shh signaling (PubMed:22883145).
Similarity : Belongs to the tectonic family.
Database links : UniProtKB/Swiss-Prot: Q6NUS6.2
结构蛋白家族3抗体品牌具有全、新、优、品、好四大特点：
全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。
新：产品更新速度较快，基本上每周都有新产品出现。
优：产品质量好，投诉比较少。
好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
我们提供的标记服务，可根据您科研的需求，满足您的需要，质量保证，价格合理。
一、标记流程
委托标记服务，请下载并详细填写《委托标记申请单》，待我公司标记室技术人员研究、确认后答复，并办理委托标记事宜。
二、各种标记物制备的收费标准（RMB）
我们不但提供抗体和大分子蛋白的标记服务，还提供小分子多肽及小分子蛋白的各种标记服务，提供标记化合物的服务（此化合物必须适用于标记），价格另议。
一抗和二坑的区别：
第一抗体就是平常所说的抗体，即能和抗原特异性结合。
第二抗体是能和抗体结合的，即抗体的抗体。主要用于检测抗体的存在。
一抗是针对抗原的抗体，二抗是针对一抗的抗体。即抗体也可以充当抗原刺激机体产生抗体。也就是说，抗原进入机体刺激机体免疫系统产生免疫应答，由B细胞可以产生与相应抗原发生特异性结合的特殊蛋白质。
一抗二抗都是一种可以特异结合别的物质的基团，而且一抗可以至少结合两种其他基团（底物和二抗）。
一抗：可以特异结合底物，就是识别出我们想要检测的东西。一抗和底物结合与否用肉眼是看不出来的。
二抗：可以和一抗结合，并带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），作用是检测一抗。 如果一抗自己带有可以被检测出的标记(如带荧光、放射性、化学发光或显色基团），则不需要二抗。但这样成本很高，因为一种一抗只识别一种底物。所以如今的设计一般是二抗带上可检测标记，再来检测一抗。而一抗识别底物。这样，当一抗结合到底物上，就可以通过二抗检测出来。
Anti-VCAM-1/CD106 /FITC 荧光素标记血管内皮细胞粘附分子抗体IgGMulti-class antibodies规格： 0.2ml
CD34 CD34抗原(细胞表面的唾液粘蛋白)Multi-class antibodies规格： 0.5mg
CXCL10趋化因子10/干扰素诱导蛋白10抗体 Anti-CXCL10/IP-10 0.1ml
StAR 英文名称： 促黄体激素诱导蛋白抗体 0.2ml
Emx1 英文名称： 有脊椎动物脑发育相关蛋白Emx1抗体 0.2ml
Rhesus antibody Rh Phospho-HER2(Ty21/1222) 化HER2受体抗体 规格 0.1ml
CD34 CD34抗原(细胞表面的唾液粘蛋白)Multi-class antibodies规格： 0.5mg
SLC33A1(Acetyl-coenzyme A transportor 1) 乙酰辅酶A转运蛋白1抗原Multi-class antibodies规格： 0.5mg
Anti-BKCa channels 激活通道蛋白抗体Multi-class antibodies规格： 0.2ml
Rhesus antibody Rh PG-C/Pepsinogen 2 胃蛋白酶原C抗体 规格 0.1ml
EMA 浓缩液 0.1ml 进口分装
Tap1 英文名称： ATP结合转运因子1抗体 0.2ml
CD170 英文名称： 唾液酸结合性免疫球蛋白样凝集素5抗体 0.1ml
Anti-BKCa channels 激活通道蛋白抗体Multi-class antibodies规格： 0.2ml
Rabbit Anti-horse IgM/PE-Cy5.5 PE-Cy5.5标记的兔抗马IgM 0.1ml
FBXL20 英文名称： FBXL20蛋白抗体 0.2ml
兔抗人鸟苷三酶-发动蛋白2抗体 Anti-Dynamin 2 0.1ml
Anti-Phospho-PDGF Receptor alpha (Tyr754) /FITC 荧光素标记化血小板源性生长因子受体-α抗体IgGMulti-class antibodies规格： 0.2ml
Rhesus antibody Rh phospho-TNIK(Ser769) 化TRAF2和NCK激酶相互作用蛋白抗体 规格 0.1ml
Rabbit Anti-chi IgG/FITC 荧光素标记兔抗鸡IgGMulti-class antibodies规格： 0.3ml
Dami(人巨核细胞白血病细胞) 5×106cells/瓶×2
CCCSCK
PTPRC Others Mouse 小鼠 CD45 / PTPRC 人细胞裂解液 (阳性对照)
8910PM细胞，人卵巢癌细胞 小鼠细胞,EMT6细胞 肾小管上皮细胞Many types of cells包装：5 × 105次方(1ml)
CL-0068COS-1(非洲绿猴SV转化的肾细胞)5×106cells/瓶×2
HTEpC Pellet 人类气管上皮细胞团块 > 1 mio.cells 人骨骼肌细胞cDNAHSkMC cDNA
骨骼肌细胞培养基SkMCM
REG1A Others Cynomolgus 食蟹猴 REG1A / PSPS 人细胞裂解液 (阳性对照)
人胚胎，皮肤，肌肉;M-22
HNE2-LMP1/2细胞，人鼻咽癌细胞系 小鼠肝癌细胞,H22细胞 CM-H071人肾动脉平滑肌细胞完全培养基100mL
OS-RC-2(人肾癌细胞) 5×106cells/瓶×2
Promocell C-27101 Chondrocyte Growth Medium, 软骨细胞生长培养基(即用型) 500ml
结构蛋白家族3抗体品牌Dami(人巨核细胞白血病细胞) 5×106cells/瓶×2
CCCSCK
PTPRC Others Mouse 小鼠 CD45 / PTPRC 人细胞裂解液 (阳性对照)
8910PM细胞，人卵巢癌细胞 小鼠细胞,EMT6细胞 肾小管上皮细胞Many types of cells包装：5 × 105次方(1ml)
CL-0068COS-1(非洲绿猴SV转化的肾细胞)5×106cells/瓶×2
HTEpC Pellet 人类气管上皮细胞团块 > 1 mio.cells 人骨骼肌细胞cDNAHSkMC cDNA
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