重组小鼠趋化因子CCL2(MCP-1)

特别提示：包括重组小鼠趋化因子CCL2(MCP-1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠趋化因子CCL2(MCP-1)
英文名称：Recombinant Mouse C-C motif Chemokine 2
产品货号：JN0331
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备，目的基因编码的Gln24-Arg96表达纯化而来。

CCL2/MCP-1质量控制：＞95%(还原性SDS-PAGE)。

CCL2/MCP-1制剂：冻干品

CCL2/MCP-1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CCL2/MCP-1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CCL2/MCP-1：
C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equine, porcine, bovine and canine CCL2, respectively. Fibroblasts, glioma cells, smooth muscle cells, endothelial cells, lymphocytes and mononuclear phagocytes can produce CCL2 either constitutively or upon mitogenic stimulation, but monocytes and macrophages appear to be the major source. In addition to its chemotactic activity, CCL2 induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils that express its receptor, CCR2. Additionally, it promotes Th2 polarization in CD4+ T cells. CCL2-mediated recruitment of monocytes to sites of inflammation is proposed to play a role in the pathology of atherosclerosis, multiple sclerosis and allergic asthma.

除了重组小鼠趋化因子CCL2(MCP-1),，我公司还供应以下相关产品：


JN0288 重组人趋化因子CXCL10(IP-10) 10μg|50μg|500μg|1mg
JN0351 重组人白介素IL-1α(白细胞介素1α) 10μg|50μg|500μg|1mg
JN0425 重组人干扰素α6(IFN-α6) 10μg|50μg|500μg|1mg
JN0435 重组人肿瘤坏死因子α(TNF-a) 10μg|50μg|500μg|1mg
JN2003 重组人血红蛋白ζ(HBZ) 10μg|50μg|500μg|1mg
JN0548 重组人Vasorin 10μg|50μg|500μg|1mg
JN0598 重组人血清淀粉样P成分(SAP) 10μg|50μg|500μg|1mg
JN0605 重组人肝配蛋白A受体7(EphA7) 10μg|50μg|500μg|1mg
JN0676 重组人α-可溶性NSF附着蛋白(α-SNAP) 10μg|50μg|500μg|1mg
JN0739 重组人CDK7(细胞周期蛋白依赖性激酶7) 10μg|50μg|500μg|1mg
JN0897 重组人对羟苯基*酮酸双氧化酶(4HPPD) 10μg|50μg|500μg|1mg
JN1072 重组人NHP2(核仁蛋白家族A成员2) 10μg|50μg|500μg|1mg
JN1276 重组小鼠Acrp30(30kD脂肪细胞补体相关蛋白) 10μg|50μg|500μg|1mg
JN1351 重组人转铁蛋白(Transferrin) 10μg|50μg|500μg|1mg
JN1435 重组小鼠外异蛋白A受体(Edar) 10μg|50μg|500μg|1mg
JN1444 重组小鼠激肽释放酶7(Kallikrein-7) 10μg|50μg|500μg|1mg
JN1488 重组人小鼠大鼠Ⅲ型纤连蛋白结构域包含蛋白5(鸢尾素) Irisin(FNDC5) 10μg|50μg|500μg|1mg
JN1496 重组小鼠DDR2 10μg|50μg|500μg|1mg
JN1517 重组人IL-22(C端带IgG2 Fc标签) 10μg|50μg|500μg|1mg
JN1707 重组人Serpin G1(丝氨酸蛋白酶抑制剂G1) 10μg|50μg|500μg|1mg
JN1839 重组人LAMP1 10μg|50μg|500μg|1mg
JN1893 重组小鼠CD74 10μg|50μg|500μg|1mg
ZN1581 人cathepsin D重组蛋白 100ng
ZN1616 人Cytochrome C重组蛋白 100ng
ZN1723 人TNFR2重组蛋白 100ng