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JN0491型重组人RANK L(TRANCE)(TNFSF

11)价格
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  • ¥200 - 2140
  • 百奥莱博
  • JN0491-HLS
  • 北京
  • 2025年07月11日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      292

    • 英文名

      Recombinant Human Receptor Activator of NF-kappa-B ligand

    • 保质期

      长期

    • 供应商

      北京百奥莱博科技有限公司

    • 保存条件

      冻干蛋白置于-20℃

    特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。

    JN0491型重组人RANK L(TRANCE)(TNFSF11)价格是高品质的重组蛋白产品,由北京百奥莱博供应,用于科研实验,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人RANK L(TRANCE)(TNFSF11)等重组蛋白产品请联*(代"系")我司咨询订购。


    名称:JN0491型重组人RANK L(TRANCE)(TNFSF11)价格
    产地:国产|进口
    英文名:Recombinant Human Receptor Activator of NF-kappa-B ligand
    品牌:百奥莱博
    编号:JN0491
    规格:10μg|50μg|500μg|1mg
    本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Ile140-Asp317在N端含有His标签。

    RANK L/TRANCE/TNFSF11质量控制:>95%(还原性SDS-PAGE)


    RANK L/TRANCE/TNFSF11制剂:冻干品

    RANK L/TRANCE/TNFSF11保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    RANK L/TRANCE/TNFSF11复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于RANK L/TRANCE/TNFSF11
    CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitogen-activated protein kinases (MAPK), activating protein 1 (AP-1), and nuclear factor of activated T cells (NFATc1), resulting in the formation of multinucleated bone-resorbing osteoclasts. RANKL is widely expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoblast, mammary gland epithelial cells, prostate and pancreas.

    JN0491型重组人RANK L(TRANCE)(TNFSF11)价格外,我公司正在打折促销以下产品:

    ·重组小鼠RANK(TNFRSF11A)(CD265)
    编号:JN0509
    英文名称:Recombinant Mouse Receptor Activator of NF-kappa B
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Val31-Ser214在C端含有His标签。

    RANK/TNFRSF11A/CD265质量控制:>95%(还原性SDS-PAGE)

    RANK/TNFRSF11A/CD265制剂:冻干品

    RANK/TNFRSF11A/CD265保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    RANK/TNFRSF11A/CD265复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于RANK/TNFRSF11A/CD265
    Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member oftumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells.


    JN0491型重组人RANK L(TRANCE)(TNFSF11)价格关键词:JN0491,重组人RANK L,重组人TNFSF11,重组人RANK L蛋白,重组人TRANCE

    N-乙酰-DL-色*酸 RiboRuler Low range RNA Ladder 87-32-1
    PAGE连续蛋白上样缓冲液(5×)   5ml
    ARB13136 小鼠前列环素(PGI2)Elisa定量检测 
    1,3-二*脲 2-Deoxy-D-glucose 102-07-8
    F010111 小鼠抗玉米赤霉烯酮抗体 Monoclonal Mouse Anti-Zearalenone
    PY02-119  *化*三糖铁琼脂  250克  
    精子细胞BWW培养基储存液   500ml
    ARB10760 人抗BP180抗体(BP180-Ab)酶标法分析 Human anti-bullous pemphigoid 180 antibody,bp180-ab ELISA KIT
    CYB162012 兔抗大鼠IgG(抗血清) 0.5ml
    单宁酶 Span 60 9025-71-2
    Seliwanoff试剂   100ml
    ARB12378 大鼠乳铁传递蛋白/乳铁蛋白(LF/LTF)Elisa定量检测 Rat lactoferrin,ltf/lf ELISA KIT
    BTN90302 *化锰溶液,PCR级 MgCl2,PCR Grade
    BL1394 SABC山羊IgG-FITC/POD双标kit
    D-丝*酸 DL-Glutamic acid 312-84-5
    Ehrlich苏木素染色液   100ml|500ml
    ARB12832 小鼠弓形虫循环抗原(TCA)ELISA代测服务 
    6160-80-1 4-MUG  4-甲基伞形酮-β-D-葡糖苷酸
    ARB14119 大鼠*卫蛋白(cAlproteIn)Elisa方法检测 
    25322-68-3 PEG20000  聚乙二醇
    JN0491型重组人RANK L(TRANCE)(TNFSF11)价格关键词:JN0491,重组人RANK L,重组人TNFSF11,重组人RANK L蛋白,重组人TRANCE


    ·重组人细胞周期蛋白依赖型激酶2(CDK2)
    编号:JN1986
    英文名称:Recombinant Human Cyclin-Dependent Kinase 2
    规格:10μg|50μg|500μg|1mg
    本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu298在N端含有His标签。

    CDK2质量控制:>95%(还原性SDS-PAGE)

    CDK2制剂:液体

    CDK2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

    关于CDK2
    Cyclin-dependent kinase 2 (CDK2) belongs to the cyclin-dependent kinase of Ser/Thr protein kinase. CDK2 acts as a catalytic subunit of the cyclin dependent kinase complex, whose activity is restricted to the G1-S phage of the cell cycle, it is essential for the G1/S transition. The kinase activity of CDK2 can be regulated by the association with a cyclin subunit, its phosphorylation state and CDK inhibitors. The activation of the CDK2/cyclin complex requires the phosphorylation of Thr160 and the dephosphorylation of Try14 and Tyr15. The inhibition of CDK2-cyclin complex can also be attributed to association with p27Kip1 and p21Waf1/Cip1. The activation of CDK2 has been shown to be necessary for apoptosis of quiescent cells, such as neurons, thymocytes and endothelial cells.



    我公司正在打折促销重组蛋白全系列产品,恭候您的咨询选购JN0491型重组人RANK L(TRANCE)(TNFSF11)价格

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    图标文献和实验
    相关实验
    • Assays for Cytotoxicity

      5 (nonfunctional) &   DcR2/TNFRSF10D /TR10 (nonfunctional)   OPG/TNFRSF11B /TR1 TRANCE (OPGL)/TNFSF11 /TL

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