重组小鼠TNFRSF9

特别提示：包括重组小鼠TNFRSF9在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠TNFRSF9
英文名称：Recombinant Mouse 4-1BB ligand receptor
产品货号：JN0477
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Val24-Leu187在C端带有Fc标签。

TNFRSF9质量控制：＞95%(还原性SDS-PAGE)

TNFRSF9制剂：液体

TNFRSF9保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于TNFRSF9：
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.

除了重组小鼠TNFRSF9,，我公司还供应以下相关产品：



名称：重组人M-CSF(含His标签)
货号：JN0205
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Glu33-Arg255在C端含有His标签。

M-CSF/CSF1质量控制：＞95%(还原性SDS-PAGE)。

M-CSF/CSF1制剂：冻干品

M-CSF/CSF1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

M-CSF/CSF1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于M-CSF/CSF1：
Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.

名称：重组人平足蛋白(Podoplanin)
货号：JN0610
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala23-Leu131在C端含有His标签。

Podoplanin质量控制：＞95%(还原性SDS-PAGE)

Podoplanin制剂：

Lyophilized

Podoplanin保存：

冻干蛋白应长期保存在-20℃以下，室温也可稳定保存3周时间
复溶后的蛋白溶液可在4℃保存2～7天。
建议根据使用量，将复溶后的蛋白溶液分装冻存在-20℃以下，可储存长达3个月。

Podoplanin复溶：

打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml.
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Podoplanin：

Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn’t have any effect on amino acid transport and the aquaporin-type water channels.