重组人BDNF(脑源性神经生长因子)

特别提示：包括重组人BDNF(脑源性神经生长因子)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人BDNF(脑源性神经生长因子)
英文名称：Recombinant Human Brain-Derived Neurotrophic Factor

产品货号：重组人BDNF(脑源性神经生长因子)
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备，目的基因编码的His129-Arg247表达纯化而来。

BDNF质量控制：＞95%(还原性SDS-PAGE)。

BDNF制剂：冻干品

BDNF保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

BDNF复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于BDNF：
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson"s and Alzheimer"s disease.

除了重组人BDNF(脑源性神经生长因子),，我公司还供应以下相关产品：



名称：重组大鼠血管内皮生长因子A(VEGF-A)(VEGF164)
货号：JN0269
规格：10μg|50μg|500μg|1mg
本品由我们的酵母表达系统制备，目的基因编码的Ala27-Arg190表达纯化而来。

VEGF164质量控制：＞95%(还原性SDS-PAGE)。

VEGF164制剂：冻干品

VEGF164保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

VEGF164复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于VEGF164：
Vascular endothelial growth factor (VEGF/VEGF-A ) is originally known as vascular permeability factor (VPF). It belongs to the PDGF family with a cysteine-knot structure comprised of eight conserved cysteine residues, and reckoned as a potent mediator in the process of angiogenesis and vasculogenesis in either fetus or adult. VEGF is particularly expressed in supraoptic , paraventricular nuclei and the choroid plexus of the pituitary, and abundant in the corpus luteum of the ovary and in kidney glomeruli. The rat VEGF protein contains a putative 20 amino acids (aa) signal peptide, and alternative splicing of rat VEGF gene produces isoforms of 120, 144, 164 and 188 aa. Rat VEGF164 respectively displays 97% and 88% aa identity with that regions of mouse and human VEGF. VEGF can bind to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin, and play important roles in inducing endothelial cell proliferation, promoting cell migration, inhibiting apoptosis and inducing permeabilization of blood vessels.