重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A)

特别提示：包括重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A)
英文名称：Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor

产品货号：重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A)
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu28-Trp79在C端带有Fc标签。

TNFRSF12A质量控制：＞95%(还原性SDS-PAGE)

TNFRSF12A制剂：冻干品

TNFRSF12A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFRSF12A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFRSF12A：
Tumor necrosis factor receptor superfamily member 12A(TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14, FN14, CD266 antigen and tweak-receptor. TNFRSF12A is a single-pass type I membrane protein, including a 27 aa signal peptide, a 53 aa extracellular domain, a 21 aa transmembrane domain and a 28 aa cytoplasmic domain. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A can be induced by FGF1 and phorbol ester. TNFRSF12A binds to TWEAK/TNFSF12A to initiate a signal transduction cascade, causing different cellular responses such as cell death, cell proliferation, and angiogenesis.

除了重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A),，我公司还供应以下相关产品：



名称：重组人GPC5(带His标签)
货号：JN0233
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Glu25-Thr554在C端含有His标签。

Glypican 5质量控制：＞95%(还原性SDS-PAGE)。

Glypican 5制剂：冻干品

Glypican 5保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

Glypican 5复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于Glypican 5：
Glypican 5 is encoded by the gene GPC5, and belongs to the Glypican family. It is 572 AA at lenth, and has a natural variation on its 155 location at which ‘A’ can mutata into ‘V’. This protein mainly exist in cell membrane and is usually secreted to extracellular space to do its function such as bearing heparin sulfate. In adult, Glypican 5 is primarily expressed in the brain, and can also be detected in fetal brain, lung and liver.

名称：重组人Stratifin蛋白
货号：JN1955
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ser248表达纯化得来。

Stratifin质量控制：＞95%(还原性SDS-PAGE)

Stratifin制剂：冻干品

Stratifin保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Stratifin复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Stratifin：
Stratifin (SFN) belongs to the 14-3-3 family of proteins that act as important regulators of intracelluar signal transduction through their ability to bind specific motifs phosphorylated on serine or threonine. There are at least seven isoforms that have been identified in mammals (beta, gamma, epsilon, sigma, zeta, tau and eta). SFN can detected in many tissues, highly expressed in stratified squamous keratinizing epithelium. SFN is indicated as an epithelial cell marker and serves as a tumor suppressor whose expression can be down regulated by methylation. In addition, SFN plays a key role in maintaining the G2 checkpoint in cells and preventing mitotic death.