重组人白介素1受体α(IL-1Rα)

特别提示：包括重组人白介素1受体α(IL-1Rα)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人白介素1受体α(IL-1Rα)
英文名称：Recombinant Human Interleukin-1 Receptor Antagonist Protein

产品货号：重组人白介素1受体α(IL-1Rα)
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备，目的基因编码的Arg26-Glu177表达纯化而来。

IL-1F3/IL-1Ra质量控制：＞95%(还原性SDS-PAGE)。

IL-1F3/IL-1Ra制剂：冻干品

IL-1F3/IL-1Ra保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-1F3/IL-1Ra复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-1F3/IL-1Ra：
Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family. Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases. It binds to IL-1 receptors in competition with IL-1, but does not elicit intracellular response from this binding. Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1RN.

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