重组人钙黏蛋白(钙粘附素)(Cadherin-3)(CDH3

特别提示：包括重组人钙黏蛋白(钙粘附素)(Cadherin-3)(CDH3)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人钙黏蛋白(钙粘附素)(Cadherin-3)(CDH3)
英文名称：Recombinant Human Cadherin-3

产品货号：重组人钙黏蛋白(钙粘附素)(Cadherin-3)(CDH3)
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu25-Gly654在C端含有His标签。

Cadherin-3/CDH3质量控制：＞95%(还原性SDS-PAGE)

Cadherin-3/CDH3制剂：冻干品

Cadherin-3/CDH3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Cadherin-3/CDH3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Cadherin-3/CDH3：
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.

除了重组人钙黏蛋白(钙粘附素)(Cadherin-3)(CDH3),，我公司还供应以下相关产品：



名称：重组人白介素IL-4(白细胞介素4)
货号：JN0379
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的His25-Ser153表达纯化而来。

IL-4质量控制：＞95%(还原性SDS-PAGE)。

IL-4制剂：冻干品

IL-4保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-4复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-4：
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.