FITC标记的热休克蛋白β7抗体

FITC标记的热休克蛋白β7抗体

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  • ¥2980
  • LMAI Bio
  • LM-9854R-FITC
  • 中国/美国/欧洲
  • 2025年07月14日
  • IF=1:50-200
  • Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
  • Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-9854R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-HSPβ7/FITC

    • 抗体名

      Anti-HSPβ7/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的热休克蛋白β7抗体
    英文名称 Anti-HSPβ7/FITC
    中文名称 FITC标记的热休克蛋白β7抗体
    别    名 Cardiovascular heat shock protein; cvHsp; Heat shock 27kda protein family member 7; Heat shock protein beta 7; Heat shock protein beta-7; Hsp25 2; HspB7; HSPB7_HUMAN; Hypothetical protein flj34956; RP11-5P18.6  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 心血管  免疫学  信号转导  细胞骨架  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 19kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human HSPβ7/cvHSP
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
    产品介绍 background:
    The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.

    Subunit:
    Interacts with C-terminal domain of actin-binding protein 280. 

    Subcellular Location:
    Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

    Tissue Specificity:
    Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.

    Similarity:
    Belongs to the small heat shock protein (HSP20) family.

    Database links:

    Entrez Gene: 27129 Human

    Omim: 610692 Human

    SwissProt: Q9UBY9 Human

    Unigene: 502612 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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