- ￥600 - 1600
- Abbiotec
- 美国
- 350535
- 2025年07月13日
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- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
NFKB p105/p50 Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
0.1 mg
| 产品名称： | NFKB p105/p50 Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/nfkb-p105/p50-peptide |
| 货号： | 350535 |
| 规格： | 0.1 mg |
| 产品描述： | Nuclear factor NF-kappa-B p105/p50 subunit (NFKB1) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RelA/p65, RelB, NFKB1/p105, NFKB1/p50, Rel and NFKB2/p52. Homo- and heterodimers bind with different affinities at kappa-B sites in the DNA of their target genes. |
| 序列： | The synthetic peptide used to raise the antibody Cat. No. 200173 is selected from a sequence within the C-term region of human NFKB p105/p50. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式： | C74H116N24O23S2 |
| 分子量： | 1774 g/mol |
| 纯度： | Purity > 80% by HPLC |
| 别名： | Nuclear factor NF-kappa-B p105/p50 subunit; DNA-binding factor KBF1; EBP-1; NFKB1 |
| 形态： | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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文献和实验, Tanacetum parthenium PPM-18 Sulfasalazine TIRAP Inhibitor Peptide, Cell-Permeable TIRAP Inhibitor Peptide, Control, Cell-Permeable Withaferin A, Withania somnifera LWP1981 我做细胞抑制的时候，用过好几次SN50，觉得SN50对NFKB转录因子的核转移抑制效果不错
renamed rel A) and p50 (recently renamed NFKB1) ( 3 , 4 ). Both of these sub-units belong to the rel famtly of transcription factors with homology in the amino terminus ( 5 , 6 ). Since the original identification of these factors
激活－核转运检测试剂盒仅染色p65，不染色RelB、C-Rel、p50和p52。使用本试剂盒染色后NF-κB呈红色荧光，细胞核呈蓝色荧光.思考信号转导和检测的理论 我做了这样的回答(个人意见.大家可以讨论!)： 这种理论上来讲可行,但是实际操作可能拿不到你想要得结果,原因很简单,凭染色来判断是很难区分程度上的差异的,就比如做WB实验,经典的还是化学发光的方法,显色的方法只能得到信号比较强的蛋白,遇到信号比较弱的蛋白就误差很大了, 第二点,并不是所有能进核的蛋白都有结合DNA
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