Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
Nocistatin blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia. Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. Nociceptin is also involved in neuronal differentiation and development. Nocistatin is a 30-aa peptide processed from the prepronociceptin precursor that is cleaved in 3 chains, nocistatin, nociceptin and orphanin FQ2.
序列:
H-Glu-Gln-Lys-Gln-Leu-Gln-OH or H-EQKQLQ-OH
分子式:
C32H56N10O12
分子量:
772.86 g/mol
纯度:
Purity > 95% by HPLC
别名:
Nocistatin; PPNOC; OFQ; PNOC; Prepronociceptin
形态:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
溶解方法:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
保存方法:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.