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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
C-Peptide (Dog)
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
1 mg
| 产品名称: | C-Peptide (Dog) |
| 产品链接: | http://www.abbiotec.com/peptides/c-peptide%25252C-dog |
| 货号: | 350135 |
| 规格: | 1 mg |
| 产品描述: | The connecting peptide, or C-peptide, is a 31-aa long peptide that connects insulin A-chain to the B-chain in the proinsulin molecule. In the insulin synthesis pathway, preproinsulin is translocated into the endoplasmic reticulum of beta cells of the pancreas with an A-chain, a C-peptide, a B-chain, and a signal sequence. After signal sequence cleavage, the C-peptide is removed from the newly formed proinsulin in the Golgi apparatus leaving the A- and B-chains bound together by disulfide bonds, forming the insulin molecule. Besides a role in assembly, folding, and processing of insulin in the ER, the C-peptide is a bioactive peptide with effects on microvascular blood flow and tissue health. Because equimolar amounts of C-peptide are stored in secretory granules of the pancreatic beta cells and eventually released in the circulation, C-peptide is a marker of insulin secretion in understanding the pathophysiology of type 1 and type 2 diabetes. |
| 序列: | Dog: H-Glu-Val-Glu-Asp-Leu-Gln-Val-Arg-Asp-Val-Glu-Leu-Ala-Gly-Ala-Pro-Gly-Glu-Gly-Gly-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ala-Leu-Gln-OH or H-EVEDLQVRDVELAGAPGEGGLQPLALEGALQ-OH |
| 分子式: | C137H225N37O49 |
| 分子量: | 3174.54 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | C-peptide; insulin; INS |
| 形态: | Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验为连接肽( conneting peptide)之简写。系从胰岛素原( proinsulin)产生胰岛素时所形成的多肽。
狗(Dog;Canis familiaris) 一、生物学特性和解剖生理特点 1.狗属哺乳纲、食肉目、犬科。 2.狗具有发达的血液循环和神经系统以及大体上和人相似的消化过程,在毒理方面的反应和人比较接近,内脏与人相似。 3.狗的嗅脑、嗅觉器官和嗅神经极为发达。鼻长,鼻粘膜上布满嗅神经,能够嗅出稀释一千万分之一的有机酸,特别是对动物性脂肪酸更为敏感,狗嗅觉能力超过人的1200倍。 4.狗的听觉也很灵敏
Culture and Proliferation of Highly Purified Adult Schwann Cells from Rat, Dog, and Man
This chapter presents fast and easy protocols to obtain highly purified cultures of proliferating adult rat, canine, and human Schwann cells. Cell preparation from predegenerated adult sciatic nerves combined with the use of melanocyte growth
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