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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
Angiotensin Converting Enzyme Inhibitor Peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
5 mg
| 产品名称: | Angiotensin Converting Enzyme Inhibitor Peptide |
| 产品链接: | http://www.abbiotec.com/peptides/angiotensin-converting-enzyme-inhibitor |
| 货号: | 350049 |
| 规格: | 5 mg |
| 产品描述: | Angiotensin Converting Enzyme Inhibitor (ACE inhibitor), secreted by the Bothrops venom gland, inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it. |
| 序列: | Bothrops: H-pGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro-OH or H-pEWPRPQIPP-OH |
| 分子式: | C53H77N14O12 |
| 分子量: | 1102.29 g/mol |
| 纯度: | Purity > 95% by HPLC |
| 别名: | Angiotensin Converting Enzyme Inhibitor; bradykinin-potentiating peptide; BBP |
| 形态: | Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
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文献和实验Quantification of Angiotensin-Converting Enzyme (ACE) Activity
Angiotensin-converting enzyme (ACE) is a dipeptidyl carboxypeptidase (EC 3.4.15.1) whose physiologic action is the conversion of AI to AII, and as such, it plays an important role in the regulation of blood pressure and fluid balance. ACE
血管紧张肽 angiotensin, hypertensin 在肾脏分泌的血管紧张肽原酶的作用下,可使血浆中的血管紧张肽原变为血管紧张肽Ⅰ,后者在血中经转变酶( Converting enzyme)的作用而变为血管紧张肽Ⅱ.仅血管紧张肽Ⅲ具有激素的作用(血压上升作用和促进醛固酮分泌作用).二者均为多肽.
Gene Therapy for Hypertension: Antisense Inhibition of the Renin-Angiotensin System
to be overactive in hypertension and that are proven targets of current drug treatments. These include β1-receptors, angiotensin-converting enzyme (ACE), and angiotensin type 1 receptors (AT1R). Antisense oligonucleotides are short (12-20 bases), single strands
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