- ¥2570
- peprotech
- 300-28A
- ProSpec
- 2025年07月11日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 供应商：
上海研卉生物科技有限公司
- 英文名：
Recombinant Human GRO-gamma (CXCL3), His Tag
- 规格：
10μg
Recombinant Human SDF-1α (CXCL12)
Product Details
SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues.
Source: E.coli
Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF
AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80 ng/ml.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Pathways Implicated in Stem Cell Migration: The SDF-1/CXCR4 Axis
The hallmark of hematopoietic stem and progenitor cells (HSPCs) is their motility, which is essential for their function, such as recruitment upon demand. Stromal Derived Factor-1 (SDF-1, CXCL12) and its major receptor CXCR4 play major roles
【进展|热点】Nature Immunology：骨髓基质细胞通过细胞间接触分泌SDF-1
by regulating the nuclear localization of the transcription factor Sp1. We suggest that BMSCs form a dynamic syncytium via connexin gap junctions that regulates CXC12 secretion and the homeostasis of hematopoietic stem cells.文章简介：CXCL12（SDF-1）对造血干细胞和前体细胞的功能发育至关
Assessment of Megakaryocyte Migration and Chemotaxis
cell-derived factor 1α (SDF1α) also known as CXCL12 has been described to act as a potent chemoattractant for MKs (1, 2). This biological effect is mediated by the SDF1α receptor CXCR4 (Fusin), which is expressed on haematopoietic stem cells, MKs
技术资料暂无技术资料 索取技术资料
