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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Cyclic AMP,cAMP
- CAS号:
60-92-4
- 供应商:
上海研卉生物科技
- 库存:
大量
- 规格:
25mg
| 产品描述 |
Adenosine cyclophosphate combined with vitamin C treatment of children with viral myocarditis has exact curative effect,and it can improve cardiac function of patients and improve immune function. |
| 靶点活性 |
|
| 体外活性 |
|
| 体内活性 |
|
化学信息
| 分子量 |
329.20 |
| 分子式 |
C10H12N5O6P |
| CAS |
60-92-4 |
| 溶解度 |
H2O: ≥ 5 mg/mL (15.19 mM) DMSO: < 1 mg/mL, insoluble or slightly soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| 储存条件 |
store at -80°C |
| 备注 |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. |
| 1 mM | 3.038 ml | 15.188 ml | 30.377 ml |
| 5 mM | 0.608 ml | 3.038 ml | 6.075 ml |
| 10 mM | 0.304 ml | 1.519 ml | 3.038 ml |
| 50 mM | 0.061 ml | 0.304 ml | 0.608 ml |
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文献和实验缩写为cAMP,又称环式 AMP。正式名称为 3′, 5′一磷酸环腺苷。是环核苷酸之一。 RNA在水解时,虽也能产生 2′, 3′型的中间产物。但通常根据生理上的重要性,仅将如图所示的 3′, 5′ -环型物称为 cAMP。它广泛存在于动植物组织和细菌中,一般浓度是极低的,为 10-6 — 10-7 M。是通过局部存在于膜构造上的腺苷酸环化酶的酶促作用,从 ATP合成。它是由 E. W. Sutherland, T. W. Rall( 1957)作为肾上腺素,胰高血糖素的血糖上升作用
The Measurement of Cyclic AMP Levels in Biological Preparations
The generation of cyclic AMP (cAMP) is probably the most scrutinized of signal transduction pathways. Receptors may be linked to the generation of AMP by one of two routes. One group of receptors (such as β-adrenoceptors, A2 adenosine receptors
Cyclic AMP- Dependent Protein Kinase Activity Ratio Assay
A multitude of natural and pharmacological agents, including hormones, neurotransmitters, and phosphodiesterase inhibitors, raise intracellular cAMP levels and, in the vast majority of instances, the physiological effects are the result
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