重组人TK1(胞浆胸腺嘧啶激酶)

特别提示：包括重组人TK1(胞浆胸腺嘧啶激酶)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人TK1(胞浆胸腺嘧啶激酶)
英文名称：Recombinant Human Thymidine kinase, Cytosolic
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Asn234在C端含有His标签。

TK1质量控制：＞95%(还原性SDS-PAGE)

TK1制剂：液体

TK1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于TK1：
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5-phosphate with the help of ATP