CEA癌胚抗原抗体

CEA癌胚抗原抗体

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  • ¥860 - 1580
  • LMAI Bio
  • LM-4793M
  • 进口/国产
  • 2025年11月21日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
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  • Human
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    • 详细信息
    • 询价记录
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-4793M

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      CEA

    • 抗体名

      癌胚抗原抗体

    • 宿主

      Rabbit

    • 适应物种

      Human

    • 免疫原

      KLH conjugated synthetic peptide derived from Human CEA/CD66e/CEACAM5:531-630/702

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  

    CEA癌胚抗原抗体
    英文名称 CEA
    中文名称 癌胚抗原抗体
    别    名 Carcino Embryonic Antigen CEA; CEACAM 5; CEACAM-5; Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; CD66e; CD66e antigen; CEA; CEACAM5; DKFZp781M2392; Meconium antigen 100.  
    规格价格 50ul/860元 购买    100ul/1580元 购买        大包装/询价
    说 明 书 50ul  100ul  
    研究领域 肿瘤  干细胞  细胞类型标志物  肿瘤细胞生物标志物  
    抗体来源 Mouse
    克隆类型 Monoclonal
    克 隆 号 1E3
    交叉反应 Human, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 150-200kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from Human CEA/CD66e/CEACAM5:531-630/702 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

    Function:
    Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. 

    Subunit:
    Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. 

    Subcellular Location:
    Cell membrane; Lipid-anchor, GPI-anchor

    Tissue Specificity:
    Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

    Similarity:
    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 7 Ig-like (immunoglobulin-like) domains. 

    SWISS:
    P06731

    Gene ID:
    1048

    Database links:

    Entrez Gene: 1048 Human

    Omim: 114890 Human

    SwissProt: P06731 Human

    Unigene: 709196 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    CEA是一种胚胎性抗原,主要存在于胎儿消化道上皮组织,胰腺和肝癌中。CEA广泛存在各种上皮性肿瘤,尤其是胃肠道恶性肿瘤,CEA分布阳性类型与肿瘤的恶性度有关。CEA与EMA一样可作为上皮性恶性肿瘤的重要标记。
    产品图片 CEA癌胚抗原抗体
    Sample: HT29 Cell (Human) Lysate at 40 ug
    Primary: Anti-CEA (bsm-4793M)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
    Predicted band size: 150-200kD
    Observed band size: 180kD

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