- ¥860 - 1580
- LMAI Bio
- LM-1624M
- 进口/国产
- 2026年06月03日
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-1624M
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
CEA(B5)
- 抗体名：
癌胚抗原单克隆抗体（检测）
- 宿主：
Rabbit
- 适应物种：
Human
- 免疫原：
Human Carcino Embryonic Antigen:full length
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
50ul 100ul
CEA(B5)癌胚抗原单克隆抗体（检测）
| 英文名称 | CEA(B5) |
| 中文名称 | 癌胚抗原单克隆抗体（检测） |
| 别 名 | Carcinoembryonic antigen; Carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CD66e; CD66e antigen; CEA; CEA; CEACAM5; CEAM5_HUMAN; DKFZp781M2392; Meconium antigen 100; OTTHUMP00000199032; OTTHUMP00000199033; OTTHUMP00000199034. |
 |
Specific References (7) | bsm-1624M has been referenced in 7 publications. [IF=5.70] Yu, Qiaoling, et al. "Plasma-enhanced Antibody Immobilization for the Development of a Capillary-based Carcinoembryonic Antigen Immunosensor Using Laser-induced Fluorescence Spectroscopy." Analytical Chemistry ELISA ; Human. PubMed:23547735 [IF=5.70] Yu, Xiaoping, et al. "Motor-based Autonomous Microsensor for Motion and Counting Immunoassay of Cancer Biomarker." Analytical Chemistry (2014). other ; Human. PubMed:24731140 [IF=5.83] Zong, Chen, et al. "Chemiluminescence imaging immunoassay of multiple tumor markers for cancer screening." Analytical Chemistry 84.5 (2012): 2410-2415. other ; Human. PubMed:22320247 [IF=5.83] Ren, Kewei, et al. "Target-Driven Triple-Binder Assembly of MNAzyme for Amplified Electrochemical Immunosensing of Protein Biomarker." Analytical Chemistry (2015). other ; PubMed:25557949 [IF=3.51] Li, Rong, et al. "Sensitive detection of carcinoembryonic antigen using surface plasmon resonance biosensor with gold nanoparticles signal amplification."Talanta (2015). other ; PubMed:26048836 [IF=4.51] Wang, Jiamian, et al. "Fabrication of highly catalytic silver nanoclusters/graphene oxide nanocomposite as nanotag for sensitive electrochemical immunoassay." Analytica Chimica Acta (2016). other ; PubMed:26772127 [IF=6.41] Song, Jie, et al. "Using silver nanocluster/graphene nanocomposite to enhance photoelectrochemical activity of CdS: mn/TiO 2 for highly sensitive signal-on immunoassay." Biosensors and Bioelectronics (2016). other ; PubMed:26901458 |
| 规格价格 | 50ul/860元 购买 100ul/1580元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul |
| 研究领域 | 肿瘤 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | B5 |
| 交叉反应 | Human, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 150-200kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | Human Carcino Embryonic Antigen:full length |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M PBS(pH7.4) with 0.03% Proclin300 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. Function: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Subunit: Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor Tissue Specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Post-translational modifications: Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. Similarity: Belongs to the immunoglobulin superfamily. CEA family. Contains 7 Ig-like (immunoglobulin-like) domains. SWISS: P06731 Gene ID: 1048 Database links: Entrez Gene: 1048 Human Omim: 114890 Human SwissProt: P06731 Human Unigene: 709196 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CEA是一种胚胎性抗原，主要存在于胎儿消化道上皮组织，胰腺和肝癌中。CEA广泛存在各种上皮性肿瘤，尤其是胃肠道恶性肿瘤，CEA分布阳性类型与肿瘤的恶性度有关。CEA与EMA一样可作为上皮性恶性肿瘤的重要标记。 分子量为150-200 kDa。 该抗体与bsm-1623M（检测）（Mouse Anti-Human CEA Monoclonal）配对使用；主要用于ELISA试剂盒，胶体金试剂条制备生产都很好。大量订购可来电商议。 |
| 产品图片 |  Paraformaldehyde-fixed, paraffin embedded (liver cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CEA(B5)) Polyclonal Antibody, Unconjugated (bsm-1624M) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0024) for 20 minutes and DAB staining. |
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文献和实验相关实验
检测方法：ELISA、RIA、荧光偏振免疫测定、免疫发光技术、自动化免疫分析等。 参考值：正常情况下，血清CEA 临床意义（腺癌检测指标） （1）可作为成人结肠癌辅助诊断的重要项目，还有助于疗效评价和预后监测。 （2）作为胰腺癌、乳腺癌诊断的参考指标。医学教育|网搜集整理
癌胚抗原检测： 检测方法：ELISA、RIA、荧光偏振免疫测定、免疫发光技术、自动化免疫分析等。 参考值：正常情况下，血清CEA 临床意义（腺癌检测指标）： （1）可作为成人结肠癌辅助诊断的重要项目，还有助于疗效评价和预后监测。 （2）作为胰腺癌、乳腺癌诊断的参考指标医学教育|网搜集整理。
【摘要】对自制时间分辨免疫荧光法定量检测癌胚抗原（CEA）试剂盒进行临床应用研究，为该试剂盒临床应用及临床疗效评价提供科学依据。 方法 收集血清标本326份，用自制试剂盒按试剂盒操作说明书对血样进行测定，并以化学发光法（Roche）为对照方法，WALLAC公司的CEA时间分辨免疫测定药盒（AutoDELFATM hCEA）作为复核试验，获取相关目标实验数据，并计算得“真实性”和“可靠性”等统计学数据。 结果 以化学发光法为对照试验，其阳性符合率为95.83%，阴性符合率为98.73%，检验
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CEA(B5)癌胚抗原单克隆抗体（检测）
¥860 - 1580
