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SMAD2 Protein

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  • SignalChem
  • 加拿大
  • 2025年07月08日
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      安诺伦(北京)生物科技有限公司

    研究领域:Cancer, Neurobiology,

    存储温度:Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

    靶点/蛋白质:Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.

    来源:E.coli

    存储溶液:50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

    参考文献:1. Patel A, et al: On the mechanism of multiple lysine methyla-tion by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem. 2009 284(36):24242-56. 2. Qi J, et al: Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 289(45):31373-81.

    别名:ASH2L2

    应用:Methyltransferase Assay

    官网链接:https://www.signalchem.com/product_details.php?id=12728

    商品关键词:ASH2L Protein,A372-30BG-20,SignalChem

    简单描述:Full-length recombinant human ASH2L was expressed in E. coli cells using an N-terminal GST tag.

    Species: Human

    Tag: GST tag

    Sequence: Full length

    Genbank Number: BC015882

    Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet. 

    Molecular Weight: ~130 kDa 


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    图标文献和实验
    相关实验
    • Molecular Detection of Smad2/Smad4 Alterations in Colorectal Tumors

      and carboxy terminals of the protein. The activation of SMADs by receptors upon TGF-β binding results in the formation of hetero-oligomeric complexes and translocation to the nucleus where transcription of target genes is effected. However, some of the SMADs

    • Protein production and purification

    • Protein Electrophoresis

      character. The N- and C- terminal and T-groups of the polypeptide can be ionized, contributing to the overall charge. The protein's net electric charge is the sum of the electric charges found on the surface of the molecule as a function of the environment

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