- ¥1380 - 2200
- LMAI Bio
- LM-9560R
- 进口/国产
- 2025年12月08日
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat, Cow,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-9560R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
KRCC1
- 抗体名：
含赖氨酸卷曲螺旋蛋白1抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Cow,
- 免疫原：
KLH conjugated synthetic peptide derived from human KRCC1:161-259/259
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
100ul 200ul
| 英文名称 | KRCC1 |
| 中文名称 | 含赖氨酸卷曲螺旋蛋白1抗体 |
| 别 名 | CHBP2; cryptogenic hepatitis binding protein; Cryptogenic hepatitis-binding protein 2; KRCC1; KRCC1_HUMAN; lysine rich coiled coil 1; Lysine-rich coiled-coil protein 1. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KRCC1:161-259/259 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| PubMed | PubMed |
| 产品介绍 | background: KRCC1 is a 259 amino acid protein that is encoded by a gene located on human chromosome 2p11.2. Consisting of 237 million bases, chromosome 2 is the second largest human chromosome and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. SWISS: Q9NPI7 Gene ID: 51315 Database links: Entrez Gene: 51315 Human SwissProt: Q9NPI7 Human Unigene: 469254 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Sample: Kidney (Mouse) Lysate at 40 ug Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-KRCC1 (bs-9560R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kD Observed band size: 31 kD  Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KRCC1) Polyclonal Antibody, Unconjugated (bs-9560R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.  Paraformaldehyde-fixed, paraffin embedded (Mouse Kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KRCC1) Polyclonal Antibody, Unconjugated (bs9560R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining.  Paraformaldehyde-fixed, paraffin embedded (Mouse Brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KRCC1) Polyclonal Antibody, Unconjugated (bs9560R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining. |
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文献和实验乙型肝炎、和HBsAg阳性的患者血清中前S1蛋白，前S1抗原阴转愈早，AHB患者的疗程愈短，预后也愈好。说明前S1抗原及其抗体的检测是急性乙型肝炎的临床诊断，疗效观察和判数据预后的良好指标。 前S1蛋白的分子生物学特性 1．乙肝病毒（HBV）的基因结构 HBV为嗜肝DNA病毒，由一个不完全双链DNA组成，约3200个氨基酸。长链L含4个开放读码框架，为病毒蛋白的编码区：S区、C区、P区、X区。短链S相当于长链的50%-100%，其不固定端可被内原性DNA多聚酶延长，使病毒成为完整
一类具有舒血管作用的多肽类物质，参与血压及局部血流的调节。它的化学结构是以缓激肽（9肽）为基团的衍生物，如赖氨酸缓激肽（10肽），蛋氨酰胰激肽（11肽），总称激肽。激肽在体内分布很广，可分为血浆激肽系和组织激肽系，正常人体激肽含量甚微，血浆中约含30微克/毫升，但作用很强，激肽释放酶使激肽原分解为激肽，故又称激肽释放酶—激肽系统。激肽原是一种α球蛋白，存在于血浆和淋巴液中。在肾、胰腺、唾液腺、汗腺、消化道等器官组织内有不具活性的激肽释放酶，当其被释放到组织液中即被组织蛋白
、色氨酸、苯丙氨酸、甲硫氨酸、苏氨酸、亮氨酸、异亮氨酸及缬氨酸。这类氨基酸必须由食物，主要是蛋白质供给。动物蛋白质的营养价值一般比植物蛋白质高些，这是因为前者所含的必需氨基酸的组成和比例，都比较合乎人体的需要。食品种类多样化，可以互相补充，提高蛋白质的营养价值。如谷类蛋白质含赖氨酸较少，而色氨酸含量相对多些，豆类蛋白质含赖氨酸较多，而色氨酸较少，把这两种蛋白质混合食用，恰好补充了彼此的不足。 除组成天然蛋白质基本结构的 20种氨基酸外，还发现几种特殊的其他氨
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