Anti-Mouse CD86 (B7-2) SAFIRE Purified

Anti-Mouse CD86 (B7-2) SAFIRE

Purified
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  • ¥2625
  • Biogems
  • 美国
  • 08912-25-100 ug
  • 2025年07月14日
  • FC, FA, IHC
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    • 详细信息
    • 技术资料
    • 保存条件

      The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

    • 克隆性

      多克隆

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 应用范围

      FC, FA, IHC

    • 规格

      100 ug

    研究领域:Innate Immunity

    来源:Rat IgG2a, kappa

    存储溶液:Phosphate-buffered aqueous solution, ph7.2.

    参考文献:Hathcock, K. S., Laszlo, G., Dickler, H. B., Bradshaw, J., Linsley, P., & Hodes, R. J. (1993). Identification of an alternative CTLA-4 ligand costimulatory for T cell activation. Science, 262(5135), 905-907.Inaba, K., Witmer-Pack, M., Inaba, M., Hathcock, K. S., Sakuta, H., Azuma, M., ... & Steinman, R. M. (1994). The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. The Journal of experimental medicine, 180(5), 1849-1860.Hathcock, K. S., Laszlo, G., Pucillo, C., Linsley, P., & Hodes, R. J. (1994). Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. The Journal of experimental medicine, 180(2), 631-640.

    特异性:Mouse

    官网链接:http://www.bio-gems.com/flow-cytometry/safire-functional-antibodies/anti-mouse-cd86-safire.html

    商品关键词:Anti-Mouse CD86 (B7-2) SAFIRE Purified,08912-25-100 ug,Biogems

    简单描述:The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity.The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibits the T-cells stimulation by antigen-presenting cells. Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes.

    Clone: GL-1 (GL1)

    Format: SAFIRE Purified

    Cell Type: Monocytes and Macrophages, T Cells, B Cells, Dendritic Cells


    官网链接: www.annoron.com
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