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- Biogems
- 1117045-1g
- 美国
- 2025年07月13日
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5g
存储溶液：Metformin hydrochloride
参考文献：Evans, J. M., Donnelly, L. A., Emslie-Smith, A. M., Alessi, D. R., & Morris, A. D. (2005). Metformin and reduced risk of cancer in diabetic patients. Bmj,330(7503), 1304-1305.Hirsch, H. A., Iliopoulos, D., & Struhl, K. (2013). Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proceedings of the National Academy of Sciences, 110(3), 972-977.Viollet, B., Guigas, B., Garcia, N. S., Leclerc, J., Foretz, M., & Andreelli, F. (2012). Cellular and molecular mechanisms of metformin: an overview.Clinical science, 122(6), 253-270.
别名：Dimethylbiguanidine, Dimethylguanylguanidine, Metformin
应用：FA
官网链接：http://www.bio-gems.com/small-molecules/inhibitors/metformin-hydrochloride.html
商品关键词：Metformin hydrochloride,1117045-1g,Biogems
简单描述：Metformin is an activator of the AMPK pathway and is reported to decrease hyperglycemia by the suppression of liver glucose production. Metformin improves insulin sensitivity and lower plasma glucose levels. It is reported to promote neurogenesis and exhibits an anti-proliferative effect in cancer lines.
Chemical Name: 3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
Molecular Formula: C4H11N5 HCl
Molecular Weight: 165.6
CAS Number: 1115-70-4
Purity:≥98%
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文献和实验Guanidine Hydrochloride Purification of Proteins From SDS
Pepstatin A (2.0 mg/ml)10 ml Leupeptin (1.0 mg/ml)10 ml Aprotinin (5.0 mg/ml)(Protease Inhibitor Cocktail Sigma #P8340)Denaturation Buffer6 M guanidine hydrochloride 57.3 g G-HCl20 mM Hepes 7.9 2 ml 1M Hepes pH 7.910 mM KCl 0.074 g KCl0.5 mM DTT 100 ml 0.5 M
Guanidine Hydrochloride Purification of Proteins From SDS PAGE
(Sigma #P7626) 10 ml Pepstatin A (2.0 mg/ml) 10 ml Leupeptin (1.0 mg/ml) 10 ml Aprotinin (5.0 mg/ml) (Protease Inhibitor Cocktail Sigma #P8340) Denaturation Buffer 6 M guanidine hydrochloride 57.3 g G-HCl 20 mM Hepes 7.9 2 ml 1M Hepes pH 7.9 10 mM
Packed column subcritical and/or supercritical fluid chromatography (p-sub or pSFC) has been used as a powerful chiral separation technique, whereby a mobile phase produces low viscosity, a high diffusion coefficient, and a solvating power. P
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