- ¥780 - 2200
- LMAI Bio
- LM-8616R
- 进口/国产
- 2026年01月07日
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Mouse, Rat,
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-8616R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
alpha 1 Fetoprotein
- 抗体名：
甲胎蛋白抗体
- 宿主：
Rabbit
- 适应物种：
Mouse, Rat,
- 免疫原：
KLH conjugated synthetic peptide derived from mouse alpha 1 Fetoprotein:501-605/605
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
50ul 100ul 200ul
| 英文名称 | alpha 1 Fetoprotein |
| 中文名称 | 甲胎蛋白抗体 |
| 别 名 | Alpha Fetoprotein; Alpha-fetoprotein; AFP; alpha 1 fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; alpha fetoglobulin; alpha Fetoprotein; Alpha fetoprotein precursor; FETA; HPAFP; FETA_MOUSE. |
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 65kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse alpha 1 Fetoprotein:501-605/605 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries. Function: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Subunit: Dimeric and trimeric forms have been found in addition to the monomeric form. Subcellular Location: Secreted. Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac. Post-translational modifications: Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. Similarity: Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. SWISS: P02772 Gene ID: 11576 Database links: Entrez Gene: 174 Human Entrez Gene: 11576 Mouse Entrez Gene: 24177 Rat Omim: 104150 Human SwissProt: P02771 Human SwissProt: P02772 Mouse SwissProt: P02773 Rat Unigene: 518808 Human Unigene: 358570 Mouse Unigene: 9174 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验癌、卵巢肿瘤、恶性畸胎瘤、胰腺癌、肠癌、肺癌等患者。 产甲胎蛋白的胃癌 (alpha-fetoprotein-producing gastric carcinoma, AFPGC) 是一种相对少见的胃癌 (GC)，最早由 Bourreille 等人 [6] 于 1970 年提出，高 AFP 水平的胃癌被称为 AFPGC [7]。AFPGC 约占 GC 的 2.7~8%[8]，也有报道占 GC 的 5.1%~15%[9]。AFPGC 是指经过病理或组织学检查确诊，伴有血清 AFP 升高，并可以排除肝炎
蛋白类；化学发光测定法；定量分析 Establishment of chemiluminescent immunoassay for determination of alpha�fetoprotein FENG Yan�Ming, MA Jun�Fen, WU Biao, GUO Lan�Ying, WU Yong�Jun, LI Zhi�Tao, WU Yi�Ming 1Department of Labour Health
北京大学和海南医学院联合对肝癌细胞特异性标志物甲胎蛋白（AFP）进行长时间的研究，发现AFP具有抑制PTEN的生物学功能，导致肝癌细胞耐受全反式维甲酸诱导的凋亡，这是AFP新功能的发现。近日以题为“Alpha-fetoprotein: a new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma
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