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- Biogems
- AF-300-19-1mg
- 美国
- 2025年07月15日
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1mg
靶点/蛋白质：TQDCSFQHS PISSDFAVK IRELSDYLL QDYPVTVAS NLQDEELCG GLWRLVLAQ RWMERLKTV AGSKMQGLL ERVNTEIHF VTKCAFQPP PSCLRFVQT NISRLLQET SEQLVALKP WITRQNFSR CLELQCQPD SSTLPPPWS PRPLEATAP TA
特异性：Monkey, Mouse, Rat
官网链接：http://www.bio-gems.com/recombinant-proteins/animal-free-cytokines/animal-free-recombinant-human-flt3-ligand.html
商品关键词：Animal-Free Recombinant Human Flt3-Ligand,AF-300-19-1mg,Biogems
简单描述：Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues. Manufactured using all non-animal reagents.
Purity: Above 105% as determined by SDS-PAGE Analysis.
Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human AML5 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Cell Type: Stem Cells
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文献和实验Culturing Human Embryonic Stem Cells in Feeder-Free Conditions
Culturing Human Embryonic Stem Cells in Feeder-Free Conditions Sohyun L. McElroy1 and Renee A. Reijo Pera Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine
CD8+, CD8, and Plasmacytoid Dendritic Cell Generation In Vitro Using flt3 Ligand
in detail for the generation of the phenotypic, functional, and developmental equivalents of CD8+ , CD8− , and plasmacytoid DCs. This includes growth and purification of recombinant flt3 ligand from Chinese hamster ovary cells, isolation of bone marrow cells, and phenotypic
Cell-Free Ligand-Binding Assays for Integrin LFA-1
for alleviating inflammation and autoimmune diseases. This chapter describes cell-free assays to study the LFA-1:ICAM-1 interactions. These assays may be used for screening novel LFA-1 antagonists.
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