- ￥31147
- PeproTech
- 100-51-1MG
- 美国
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
充足
- 供应商：
PeproTech
- 英文名：
Human Epigen
- 规格：
1mg
Human Epigen (1mg)
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Product Details |
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Size |
1 mg |
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Species |
Human |
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Published Species |
Human |
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Expression system |
E. coli |
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Amino acid sequence |
AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA |
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Molecular weight |
7.9 kDa |
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Class |
Recombinant |
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Type |
Protein |
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Purity |
98% by SDS-PAGE gel and HPLC analyses. |
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Endotoxin concentration |
<1 EU/µg |
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Activity |
Determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells. The expected ED50 for this effect is 150-300 ng/ml. |
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Conjugate |
Unconjugated |
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Form |
Lyophilized |
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Purification |
purified |
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Contains |
no preservative |
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Storage conditions |
-20°C |
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Applications |
Tested Dilution |
Publications |
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Functional Assay (Functional) |
Assay-dependent |
- |
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In vitro Assay (IV) |
- |
1 Publication |
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Miscellaneous PubMed (Misc) |
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2 Publications |
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Product Specific Information
Recombinant Human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF- homologous portion of the Epigen precursor.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot- specific Certificate of Analysis
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Human Epigen Protein (100-51-1MG) in Functional |
| Bioassay analysis of Human Epigen Recombinant Protein, PeproTech® (Product # 100-51-1MG). |
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文献和实验[1]Ho J, Yang X, Nikou SA, Kichik N, Donkin A, Ponde NO, Richardson JP, Gratacap RL, Archambault LS, Zwirner CP, Murciano C, Henley-Smith R, Thavaraj S, Tynan CJ, Gaffen SL, Hube B, Wheeler RT, Moyes DL, Naglik JR. Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor. Nat Commun. 2019 May 24;10(1):2297. doi: 10.1038/s41467-019-09915-2. PMID: 31127085; PMCID: PMC6534540.
[2]Lindzen M, Ghosh S, Noronha A, Drago D, Nataraj NB, Leitner O, Carvalho S, Zmora E, Sapoznik S, Shany KB, Levanon K, Aderka D, Ramírez BS, Dahlhoff M, McNeish I, Yarden Y. Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53. Oncogene. 2021 May;40(21):3665-3679. doi: 10.1038/s41388-021-01784-8. Epub 2021 Apr 30. PMID: 33941851; PMCID: PMC8154589.
[3]Tanabe K, Inagaki A, Henmi Y, Satake M. Image-Based Profiling Can Discriminate the Effects of Inhibitors on Signaling Pathways under Differential Ligand Stimulation. SLAS Discov. 2018 Apr;23(4):330-340. doi: 10.1177/2472555217751091. Epub 2018 Jan 3. PMID: 29298398.
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