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- 详细信息
- 文献和实验
- 技术资料
- 样本:
血清、血浆
- 库存:
1
- 标记物:
心血管
- 适应物种:
人
- 应用:
ELISA
- 检测方法:
ELISA
- 检测范围:
0-2 000pmol/l (= 0-157.8 ng/ml)
- 供应商:
北京博蕾德生物科技有限公司
- 规格:
96T
s臂板蛋白4D ELISA试剂盒Semaphorin 4D ELISA|BI-20405
背景简介:
臂板蛋白4D(semaphorin 4D,SEMA4D,CD100)在许多人类肿瘤中广泛表达,其表达与人类侵袭性疾病相关。SEMA4D通常调节某些细胞的运动和分化,包括免疫系统和血管系统的细胞。在临床前肿瘤微环境中,炎性细胞和肿瘤细胞表达SEMA4D调节髓细胞和淋巴细胞的浸润、空间分布和活性。SEMA4D结合位于肿瘤微环境中髓细胞上的神经丛蛋白(plexin)受体。当SEMA4D蛋白被阻断时,可消除SEMA4D屏障。一旦屏障被突破,炎性树突状细胞和促炎性抗原提呈细胞就会迁移并渗透到肿瘤中。在临床前癌症动物模型中,用抗体阻断SEMA4D可延缓肿瘤生长,并促进持久的肿瘤排斥反应。
产品信息:
| 货号 | BI-20405 |
| 产品名称 | Soluble Semaphorin 4D ELISA |
| 检测方法 | 夹心ELISA |
| 样本量 | 10µl/well |
| 检测时间 | 3 h / 1 h / 30 min |
| 灵敏度 | 12 pmol/l (= 0.94 ng/ml) |
| 检测范围 | 0-2 000pmol/l (= 0-157.8 ng/ml) |
| 特异性 | 内源性和重组小鼠/大鼠Angiopoietin-2 |
| 准确性 | 批间差异≤ 11%CV,批内差异≤8% CV |
| 应用 | 科研 |
更多产品信息,请联系Biomedica 中国区总代理北京博蕾德生物科技有限公司
肖先生 18611095289 同微信
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文献和实验该产品被引用文献
Hypoglycaemia leads to a delayed increase in platelet and coagulation activation markers in people with type 2 diabetes treated with metformin only: Results from a stepwise hypoglycaemic clamp study. Aberer, F., Pferschy, P.N., Tripolt, N.J., Sourij, C., Obermayer, A.M., Prüller, F., Novak, E., Reitbauer, P., Kojzar, H., Prietl, B., Kofler, S., Brunner, M., Svehlikova, E., Stojakovic, T., Scharnagl, H., Oulhaj, A., Aziz, F., Riedl, R., Sourij, H., 2020. Diabetes, Obesity and Metabolism 22, 212–221.
Sandwich ELISA for the Quantification of Soluble Human Semaphorin 4D, a factor promoting skeletal metastases. Bitzer, A., Laber, A., Gadermaier, E., Wallwitz, J., Berg, G., Himmler, G., 2019, in: Osteologie. Presented at the OSTEOLOGIE 2019, Georg Thieme Verlag KG, p. V 1.8.
Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients.
Göbel, A., Kuhlmann, J.D., Link, T., Wimberger, P., Link-Rachner, C., Thiele, S., Dell’Endice, S., Furesi, G., Breining, D., Rauner, M., Hofbauer, L.C., Rachner, T.D., 2019. Journal of Bone Oncology, 16: 100237. PMID: 31011525
A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma.
Laber, A., Gadermaier, E., Wallwitz, J., Berg, G., Himmler, G., 2019. Anal. Biochem. 574, 15–22.
PMID: 30879960
Sandwich ELISA for the Quantification of Soluble Human Semaphorin 4D, a factor promoting skeletal metastases. Bitzer, A., Laber, A., Gadermaier, E., Wallwitz, J., Berg, G., Himmler, G., 2019, in: Osteologie. Presented at the OSTEOLOGIE 2019, Georg Thieme Verlag KG, p. V 1.8.
Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients.
Göbel, A., Kuhlmann, J.D., Link, T., Wimberger, P., Link-Rachner, C., Thiele, S., Dell’Endice, S., Furesi, G., Breining, D., Rauner, M., Hofbauer, L.C., Rachner, T.D., 2019. Journal of Bone Oncology, 16: 100237. PMID: 31011525
A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma.
Laber, A., Gadermaier, E., Wallwitz, J., Berg, G., Himmler, G., 2019. Anal. Biochem. 574, 15–22.
PMID: 30879960
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臂板蛋白4D ELISA试剂盒Semaphorin 4D ELISA|BI-20405
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