- ￥1076 - 3700
- MedChemExpress(MCE)
- 美国
- HY-100526
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/2 mg/5 mg/10 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1924.0 |
|---|---|---|---|
| 规格： | 2 mg | 产品价格： | ￥1076.0 |
| 规格： | 5 mg | 产品价格： | ￥2088.0 |
| 规格： | 10 mg | 产品价格： | ￥3700.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
XMU-MP-1
CAS No. : 2061980-01-4
MCE 国际站：XMU-MP-1
产品活性：XMU-MP-1是可逆和选择性的 MST1/2 抑制剂，IC50 分别为71.1和38.1 nM。
研究领域：Stem Cell/Wnt
作用靶点：Hippo (MST)
In Vitro: At concentrations ranging from 0.1 to 10 μM, XMU-MP-1 reduces the phosphorylation of endogenous MOB1, LATS1/2, and YAP in HepG2 cells in a dose-dependent manner. XMU-MP-1 treatment inhibits hydrogen peroxide-stimulated MOB1 phosphorylation and MST1/2 autophosphorylation in a variety of cell lines, including mouse macrophage-like cells, human osteosarcoma, human colorectal adenocarcinoma cells. XMU-MP-1 blocks MST1/2 kinase activities, thereby activating the downstream effector Yes-associated protein and promoting cell growth. XMU-MP-1 can potently and reversibly suppress the activities of kinases MST1/2 and enhance their downstream YAP activation in cells.
In Vivo: XMU-MP-1 displays excellent in in vivo pharmacokinetics and is able to augment mouse intestinal repair, as well as liver repair and regeneration, in both acute and chronic liver injury mouse models at a dose of 1 to 3 mg/kg via intraperitoneal injection. XMUMP-1 treatment exhibits substantially greater repopulation rate of human hepatocytes in the Fah-deficient mouse model than in the vehicle-treated control, indicating that XMU-MP-1 treatment might facilitate human liver regeneration.
相关产品：Bioactive Compound Library Plus | Stem Cell Signaling Compound Library | Anti-Cancer Compound Library | Peptidomimetic Library | Anti-Aging Compound Library | Targeted Diversity Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Heterocyclic Compound Library | Highly Selective Inhibitors Library | I3MT-3 | EMT inhibitor-1 | IHMT-MST1-58
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验经常看到很多大牛的 PPT 里面有很多极具视觉性的 Animation，自己平时也看到很多生物医学相关的国外的 Video，但是以上两种大多只能在线观看，不能下载（若知道下载方法的请忽略此文），经过探索及使用，现将相关下载方法推荐给各位，希望对需要的人有用。01 推荐的国外生物学视频网站1. BioInteractiveBioInteractive2. PBS Learning MediaPBS LearningMedia以上两个网站都包含了大量生物学相关的 Animation, Video
18/19 DNA (2686 bp) = 1.77 µg 1 pmol pBR322 DNA (4361 bp) = 2.88 µg 1 pmol M13mp18/19 DNA (7249 bp) = 4.78 µg 1 pmol λDNA (48502 bp) = 32.01 µg 1.0 kb DNA = 333个氨基酸的编码量≈ 37,000 道尔顿蛋白质 10,000道尔顿蛋白质≈270 bp DNA 50,000道尔顿蛋白质≈ 1.35 kb
核酸、核苷酸的基本换算 1．核酸的换算： (1)摩尔数与质量： 1 μg 1,000bp DNA = 1.52 pmol 1 μg pUC18/19 DNA (2,688bp) = 0.57 pmol 1 μg pBR322 DNA (4,361bp) = 0.35 pmol 1 μg SV40 DNA (5,243bp) = 0.29 pmol 1 μg FX174 DNA (5,386bp) = 0.28 pmol 1 μg M13mp18/19 DNA (7.250bp
技术资料暂无技术资料 索取技术资料
