CRLF2胸腺基质淋巴细胞生成素受体抗体

CRLF2胸腺基质淋巴细胞生成素受体抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-4652R
  • 进口/国产
  • 2025年11月24日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-4652R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      CRLF2

    • 抗体名

      胸腺基质淋巴细胞生成素受体抗体

    • 宿主

      Rabbit

    • 适应物种

      Mouse, Rat,

    • 免疫原

      KLH conjugated synthetic peptide derived from mouse CRLF2:251-350/370 <Cytoplasmic>

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    CRLF2胸腺基质淋巴细胞生成素受体抗体
    英文名称 CRLF2
    中文名称 胸腺基质淋巴细胞生成素受体抗体
    别    名 CRL 2; CRL2; CRLF 2; Crlf2; CRLF2_MOUSE; CRLF2Y; Cytokine receptor CRL2 precusor; Cytokine receptor like 2; Cytokine receptor like factor 2; Cytokine receptor like factor 2 precursor; Cytokine receptor-like 2; Cytokine receptor-like factor 2; IL XR; IL-XR; ILXR; Thymic stromal derived lymphopoietin receptor; Thymic stromal lymphopoietin protein receptor; Thymic stromal lymphopoietin receptor; TSLP receptor; TSLPR.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  免疫学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Mouse, Rat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 36kDa
    细胞定位 细胞膜 分泌型蛋白 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from mouse CRLF2:251-350/370 <Cytoplasmic>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
    Tissue specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.

    Function:
    Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.

    Subunit:
    Heterodimer of CRLF2 and IL7R.

    Subcellular Location:
    Isoform 1: Cell membrane; Single-pass type I membrane protein.
    Isoform 3: Cell membrane; Single-pass type I membrane protein.
    Isoform 2: Secreted. 

    Tissue Specificity:
    Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells.

    Similarity:
    Belongs to the type I cytokine receptor family. Type 5 subfamily.
    Contains 1 fibronectin type-III domain.

    SWISS:
    Q8CII9

    Gene ID:
    57914

    Database links:

    Entrez Gene: 64109 Human

    Entrez Gene: 57914 Mouse

    Entrez Gene: 171499 Rat

    Omim: 300357 Human

    Omim: 400023 Human

    SwissProt: Q9HC73 Human

    SwissProt: Q8CII9 Mouse

    SwissProt: Q8R4S8 Rat

    Unigene: 287729 Human

    Unigene: 35771 Mouse

    Unigene: 177948 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 CRLF2胸腺基质淋巴细胞生成素受体抗体
    Sample:kidney(mouse) Lysate at 40 ug
    Primary: Anti-CRLF2 (bs-4652R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 36kD
    Observed band size: 36 kD

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