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- 2025年11月14日
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- 详细信息
- 技术资料
- 保质期：
recombinant human IL-27 protein
- 英文名：
IL-27
- 库存：
1-2周
- 供应商：
上海研卉生物
- 规格：
10ug
科研实验用白介素27重组蛋白，recombinant human IL-27 protein
Activity
15-200 ng/mL in OCI-AML5 cells
Species Reactivity
human
Purity
>95%
Technical Specifications
Background
IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases (PMID: 22608254;16081786;16670296;16906167)
Synonyms
IL 27, IL 27 A, IL 27 subunit alpha, IL 27A, IL27, IL-27, IL27 A, IL27A, IL27p28, IL30, interleukin 27, Interleukin 27 subunit alpha, p28
| Molecular Mass | 25 and 30 kDa reduced and non-reduced, heterodimer, glycosylated |
| Formulation | 1x PBS, See Certificate of Analysis for details |
| Species Reactivity | human |
| GeneID | 246778 |
| Species | Human |
| Expression | HEK293 |
| Activity | 15-200 ng/mL in OCI-AML5 cells |
| Purity | >95% |
| Endotoxin | <1 EU/μg |
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