相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-19559R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
OATP2
- 抗体名:
肝特异性有机阴离子转运蛋白LST1抗体
- 宿主:
Rabbit
- 适应物种:
Human
- 免疫原:
KLH conjugated synthetic peptide derived from human OATP2:101-200/691
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | OATP2 |
| 中文名称 | 肝特异性有机阴离子转运蛋白LST1抗体 |
| 别 名 | Liver-specific organic anion transporter 1; LST-1; LST1; OATP-2; OATP-C; OATP1B1; OATPC; SLC21A6; SLCO1B1; SO1B1_HUMAN; Sodium-independent organic anion-transporting polypeptide 2; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 76kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OATP2:101-200/691 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009] Function: Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. May play an important role in the clearance of bile acids and organic anions from the liver. Subcellular Location: Basolateral cell membrane. Detected in basolateral membranes of hepatocytes. Tissue Specificity: Highly expressed in liver. Not detected in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. Similarity: Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain. SWISS: Q9Y6L6 Gene ID: 10599 Database links: Entrez Gene: 10599 Human Omim: 604843 Human SwissProt: Q9Y6L6 Human Unigene: 449738 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 | ![]() Tissue/cell: human hepatoma carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-OATP2 Polyclonal Antibody, Unconjugated(bs-19559R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验颜宁团队 2021 首秀+ 2020 年度文章赏析,看大牛如何玩转结构生物学!
2020 年结构生物学突飞猛进,取得了令人瞩目的成就! 疫情初期,面对新型的冠状病毒,结构生物学家们争先恐后的对病毒结构进行了深度解析,一系列的研究成果为后续的抗体检测、中和抗体、疫苗研发等提供了坚实的结构基础; 2020 年 10 月,Nature 「背靠背」发表文章,将人们利用冷冻电镜的观测精度扩展到了原子分辨率级别,高达 1.2 Å 的分辨率下,蛋白原子结构清晰可见,与电子密度图完美契合; 2020 年 12 月,由 Google 旗下 DeepMind 开发的 AI 系统
总蛋白(包括质膜和细胞器膜蛋白),但费时费力。目前,有一种最新型有效的膜蛋白提取工具,并具有高纯度、高特异性、高载量温和提取的优点。是基于1980年科学家在牛眼视网膜中发现的一种命名为Rho1D4的氨基酸序列以及其对应的抗体来作为亲和标签纯化膜蛋白取得了非常好的效果,将Rho1D4抗体链接在琼脂糖或磁珠上,用于亲和层析带有Rho1D4标签的膜蛋白,能近乎完美的解决这些研究难题。1) 什么是Rho1D4?Rho1D4是指在牛眼视网膜细胞内的牛视紫红质C端的最后九位氨基酸。Rho1D4得名于与该序列特异性
蛋白浓缩方法基本有: 丙酮沉淀法;免疫沉淀法;三氯醋酸沉淀法;硫酸铵沉淀法;(低温)有机溶剂沉淀法;聚乙二醇沉淀法;超滤法;透析法;离子交换层析和冷冻干燥法…… 1,丙酮沉淀法;三氯醋酸沉淀法 试验要求的仪器简单,但是常常导致蛋白质变性。 2,免疫沉淀法:得有特异性抗体! 3,硫酸铵沉淀法:利用高浓度盐将蛋白质析出(盐析) 选择硫酸按是因为:盐析有效性,pH范围广,溶解度高,溶液散热少,经济! 4,(低温)有机溶剂沉淀法:强调低温(0-4度
技术资料暂无技术资料 索取技术资料










