PSMD11 26S蛋白酶体非ATP酶调节亚基11抗体

PSMD11 26S蛋白酶体非ATP酶调节亚基11抗体

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  • ¥1380 - 2200
  • LMAI Bio
  • LM-19466R
  • 进口/国产
  • 2025年12月16日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-19466R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      PSMD11

    • 抗体名

      26S蛋白酶体非ATP酶调节亚基11抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,

    • 免疫原

      KLH conjugated synthetic peptide derived from human PSMD11:301-400/422

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      100ul  200ul

    PSMD11 26S蛋白酶体非ATP酶调节亚基11抗体
    英文名称 PSMD11
    中文名称 26S蛋白酶体非ATP酶调节亚基11抗体
    别    名 26S proteasome non-ATPase regulatory subunit 11; 26S proteasome regulatory subunit 9; 26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit RPN6; 26S proteasome regulatory subunit S9; MGC3844; p44.5; protease 26S, subunit, 9; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; proteasome 26S subunit, non-ATPase, 11; PSD11_HUMAN; PSMD 11; PSMD11; Rpn6; S9.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  泛素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 38kDa
    细胞定位 细胞核 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human PSMD11:301-400/422 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

    Function:
    Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

    Subcellular Location:
    Nucleus. Cytoplasm > cytosol.

    Tissue Specificity:
    Highly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.

    Post-translational modifications:
    Phosphorylated by AMPK.

    Similarity:
    Belongs to the proteasome subunit S9 family.
    Contains 1 PCI domain.

    SWISS:
    O00231

    Gene ID:
    5717 

    Database links:

    Entrez Gene: 513461 Cow

    Entrez Gene: 480610 Dog

    Entrez Gene: 5717 Human

    Entrez Gene: 69077 Mouse

    Entrez Gene: 303353 Rat

    Entrez Gene: 322265 Zebrafish

    Omim: 604449 Human

    SwissProt: Q2KI42 Cow

    SwissProt: O00231 Human

    SwissProt: Q8BG32 Mouse

    SwissProt: F1LMZ8 Rat

    Unigene: 443379 Human

    Unigene: 260539 Mouse

    Unigene: 11861 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

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