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- 艾美捷LifeSensors
- LSS-SI9830
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
MLN-4924,NEDD8-activating enzyme inhibitor
- 供应商：
武汉艾美捷
- 规格：
1mg
产品名称：MLN4924，Nedd8激活酶抑制剂MLN-4924,NEDD8-activating enzyme inhibitor
产品货号：LSS-SI9830
产品规格：1mg
产品描述：含有MLN4924的活性成分，可作为NEDD8活化酶（NAE）的底物辅助抑制剂。NAE激活NEDD8（神经前体细胞表达，发育上调节8）以缀合多种泛素E3连接酶。NEDD8-MLN4924加合物结合并抑制NAE，这可能导致肿瘤细胞增殖和存活的抑制。该可透过细胞的化合物选择性地抑制NAE活性并导致NEDD8途径的抑制。【CAS：905579-51-3】
保存建议：MLN4924，Nedd8激活酶抑制剂建议收到产品后置于-20℃中保存。
背景资料：MLN4924是Nedd8激活酶(NAE)的小分子抑制剂，产生一个酶催化的共价的NEDD8-MLN4924加合物。
点击：MLN4924，Nedd8激活酶抑制剂MLN-4924,NEDD8-activating enzyme inhibitor查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。
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文献和实验and thereafter determining the product of the enzyme-mediated reaction. Enzyme inhibition can be read out directly from the reduced peak area of product in comparison with that in the reference electropherogram obtained in the absence of any inhibitor.
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS), the most common cancer in AIDS patients. All herpesviruses express a conserved dimeric serine protease that is required for generating
A Conformationally Restricted -Strand HIV Protease Inhibitor
after the potent HIV protease inhibitor 2 , which together with a series of related derivatives was developed at Abbott Laboratories ( 11 ). This pseudopeptide contains a symmetrical diamino diol motif 8 (Fig. 2 ) flanked by Cbz-protected valine residues
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