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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
Lactacystin,proteasome inhibitor
- 供应商:
武汉艾美捷
- 规格:
200ug
产品名称:乳胞素,蛋白酶体抑制剂Lactacystin,proteasome inhibitor
产品货号:LSS-SI9760
产品规格:200ug
产品描述:Lactacystin是一种细胞渗透性,有效和选择性蛋白酶体抑制剂,可与20S蛋白酶体的催化β-亚基不可逆地结合,抑制其胰凝乳蛋白酶样和胰蛋白酶样活性,还抑制NF-κB活化(IC50 =10uM)。【CAS:133343-34-7】
保存建议:乳胞素,蛋白酶体抑制剂建议收到产品后置于-20℃中保存。
背景资料:UPS(Ubiquitin-proteasome system,泛素-蛋白酶体系统)是细胞内蛋白质降解的多组分系统,它参与细胞的生长、分化,DNA复制与修复,细胞代谢、免疫反应等重要生理生化过程。蛋白酶体(2.5MDa):由2个19S和1个20S亚单位组成的桶状结构,19S为调节亚单位,位于桶状结构的两端,识别多聚泛素化蛋白并使其去折叠。19S亚单位上还具有一种去泛素化的同功肽酶,使底物去泛素化。20S为催化亚单位,位于两个19S亚单位的中间,其活性部位处于桶状结构的内表面,可避免细胞环境的影响。
点击:乳胞素,蛋白酶体抑制剂Lactacystin,proteasome inhibitor查看更详细产品说明,更多应用、储存、价格、货期等信息请致电垂询中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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文献和实验Similar to the trypsin inhibitor, the chymotrypsin inhibitor also decreases protein degradability in the intestine, resulting in lower availability of amino acids and peptides for production purposes. This adversely affects growth
city directed primarily toward trypsin (Kunitz inhibitor), and (2) those that have a molecular weight of only 6000 to 10,000 Da with a high proportion of cystine residues and are capable of inhibiting chymotrypsin as well as trypsin at independent
-amylases of diverse origin. Three major groups of α-amylase have been characterized, based on molecular weight: 60,000, 24,000, and 12,500 Da. The inhibitor forms a complex with amylase. The complex formation can inactivate the amylase and in turn cause
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