5-Bromo-2′-deoxyuridine,5溴- 2'

5-溴-2′-脱氧尿苷

5-Bromo-2′-deoxyuridine

BioUltra, ≥99%

别名: 5-BrdU, 5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶, 5-溴脱氧尿苷, BUdR

General description

5′-Bromo-2-deoxyuridine (BrdU) is a carcinogen that may be absorbed by skin or inhalation. BrdU solutions are sensitive to light.

Application

5-Bromo-2′-deoxyuridine has been used:
• to label proliferating cells in pregnant mice in cell proliferation assay
• to study the time course of cell proliferation at various times following ischemia , to confirm re-entry of MKI67+ cells in cell cycle to germ cells
• in 5′-Bromo-2′Deoxyuridine (BrdUrd) staining of fibroblasts

包装

1 g in poly bottle

50, 250 mg in poly bottle

Biochem/physiol Actions

5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
 

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