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2462
- 供应商:
北京博蕾德生物科技有限公司
- 规格:
2557T/96T
| 规格: | 2557T | 产品价格: | ¥2461.0 |
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文献和实验Use of RNA Interference to Investigate Cytokine Signal Transduction in Pancreatic Beta Cells
to the cytokines interleukin(IL)-1β + interferon(IFN)-γ or to tumor necrosis factor(TNF)-α + IFN-γ induces beta cell dysfunction and ultimately apoptosis. The transcription factors NF-κB and STAT1 are key regulators of cytokine-induced beta cell death
microRNA detection platform to identify genes that are induced by IFNα in hepatoma- or melanoma-derived human tumor cell lines. Despite the enormous differences in expression levels between these models, we were able to identify microRNAs
of metalloproteinase; TNF, tumor necrosis factor. IL-33 signaling occurs via the ST2L receptor. Binding of IL-33 to ST2L induces the recruitment of IL-1RAcP and activation of intraCell ular signaling pathways including MyD88 and TRAF6-dependent activation
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