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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-17671R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
SPINK4
- 抗体名:
胃肠肽SPINK4抗体
- 宿主:
Rabbit
- 适应物种:
Human
- 免疫原:
KLH conjugated synthetic peptide derived from human SPINK4:27-86/86
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
100ul 200ul
| 英文名称 | SPINK4 |
| 中文名称 | 胃肠肽SPINK4抗体 |
| 别 名 | Gastrointestinal peptide; ISK4_HUMAN; PEC 60; PEC60; Peptide PEC-60 homolog; Serine peptidase inhibitor Kazal type 4; Serine protease inhibitor Kazal-type 4; SPINK4. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 细胞生物 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 6.7kDa |
| 细胞定位 | 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPINK4:27-86/86 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: SPINK4 is an 86 amino acid secreted protein containing one kazal-like domain, which has been suggested to play a role in central nervous system disorders associated with dopamine dysregulation. Expressed in the gastrointestinal tract, central nervous system, bone marrow and peripheral blood, SPINK4 is moderately expressed in spleen and is encoded by a gene mapping to human chromosome 9p13.3. Human chromosome 9 houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Subcellular Location: Secreted. Similarity: Contains 1 Kazal-like domain. SWISS: O60575 Gene ID: 27290 Database links: Entrez Gene: 27290 Human Omim: 613929 Human SwissProt: O60575 Human Unigene: 555934 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验-ENK)和亮氨酸脑啡肽(L-ENK)两种。脑啡肽与阿片受体常相伴而存在,微电泳啡肽可命名大脑皮层、纹状体和中脑导水管周围灰质神经元的放电受到抑制。脑啡肽在脊髓背角胶质区浓度很高,它可能是调节痛觉纤维传入活动的神经递质。 脑内还有胃肠肽存在,例如胆囊收缩素(CCK)、促胰液素、胃泌素、胃动素、血管活性肠肽、胰高血糖素等。CCK有抑制摄食行为的作用。许多胆碱能神经元中含有血管活性肠肽,它可能具有加强乙酰胆碱作用的功能。此外,脑内还有其他肽类物质,例如P物质、神经降压素、血管紧张素Ⅱ
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