Thymosin beta 4 antibody

Thymosin beta 4 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-9870R
  • 中国/美国/德国
  • 2025年12月17日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200
  • Rabbit
  • Human, Mouse, Rat,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-9870R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      Thymosin beta 4 antibody

    • 抗体名

      胸腺素β4抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat,

    • 免疫原

      KLH conjugated synthetic peptide derived from human Thymosin beta 4:37-44/44

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    Thymosin beta 4 antibody
    中文名称 胸腺素β4抗体
    别    名 Tβ4; FX; Hematopoietic system regulatory peptide; Prothymosin beta 4; PTMB 4; PTMB4; Seraspenide; T beta 4; T beta-4; TB4X; THYB 4; Thyb4; Thymosin beta 4; Thymosin beta 4 X chromosome; Thymosin beta 4 X linked; TMSB 4; TMSB4; TMSB4X; TYB4_HUMAN.  Tβ-4; Tβ 4.
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 心血管  信号转导  细胞骨架  细胞外基质  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 4.8kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Thymosin beta 4:37-44/44 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Proteins in the thymosin beta family are highly conserved polar peptides that bind monomeric Actin and thereby inhibit Actin polymerization. These proteins act as the main intracellular G-Actin sequestering peptides. The most abundant thymosin beta family member in mammalian cells and tissues is thymosin beta-4 (Tbeta-4), also designated Seraspenide. T beta-4 participates in several cellular events including cancerogenesis, apoptosis, angiogenesis, blood coagulation and would healing. Specifically, T beta-4 promotes cell migration and adhesion, accelerates wound healing and reduces inflammation, and becomes upregulated in a wide variety of human carcinomas. Due to the effects of T beta-4 in these events, it may become a protein of significant biological and pharmaceutical relevance.

    Function:
    Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
    Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase.

    Subcellular Location:
    Cytoplasm, cytoskeleton.

    Tissue Specificity:
    Originally found in thymus but it is widely distributed in many tissues.

    Similarity:
    Belongs to the thymosin beta family.

    SWISS:
    P62327

    Gene ID:
    7114

    Database links:

    Entrez Gene: 7114 Human

    Entrez Gene: 19241 Mouse

    Entrez Gene: 81814 Rat

    Omim: 300159 Human

    SwissProt: P62327 Horse

    SwissProt: P62328 Human

    SwissProt: P20065 Mouse

    SwissProt: P62329 Rat

    SwissProt: Q0P5V6 Rat

    Unigene: 437277 Human

    Unigene: 142729 Mouse

    Unigene: 409203 Mouse

    Unigene: 168067 Rat

    Unigene: 2605 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 Thymosin beta 4 antibody
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Thymosin beta 4) Polyclonal Antibody, Unconjugated (bs-9870R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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