GTPBP9 antibody

GTPBP9 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-9554R
  • 中国/美国/德国
  • 2025年11月07日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Cow, Sheep, Fruit Fly,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-9554R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      GTPBP9 antibody

    • 抗体名

      鸟嘌呤核苷酸结合蛋白9抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Cow, Sheep, Fruit Fly,

    • 免疫原

      KLH conjugated synthetic peptide derived from human GTPBP9:151-250/396

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    GTPBP9 antibody
    中文名称 鸟嘌呤核苷酸结合蛋白9抗体
    别    名 DNA damage-regulated overexpressed in cancer 45 protein; DOC45; GBP45; GTP-binding protein 9 (putative); GTP-binding protein 9; GTP-binding protein PTD004; homologous yeast-44.2 protein; Obg like ATPase 1; Obg-like ATPase 1; OLA1; OLA1_HUMAN; PTD004.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  免疫学  G蛋白信号  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Sheep, Fruit Fly, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 45kDa
    细胞定位 细胞核 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human GTPBP9:151-250/396 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    GTP-binding protein 9 is a 396 amino acid protein that belongs to the Obg-related GTPase family under the translation factors (TRAFAC) class. Originally thought to only have GTPase activity, Obg-related GTPase family members have been shown to also have ATPase activity. In Homo sapians, GTPBP9 exhibits a preference for binding ATP over GTP, with GTP binding occuring only at high nucleotide concentration. One cause for ATP affinity and GTP discrimination is thought to be a substitution of glutamine for a hydrophobic amino acid in Obg-related family members; this is the same substitution that inactivates Ras-like GTPases. GTPBP9 contains a C-terminal TGS domain that binds to ligands and an N-terminal G domain which binds nucleotides. GTPBP9 is expressed as three isoforms produced by alternative splicing.

    Function:
    Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.

    Subunit:
    Monomer. 

    Subcellular Location:
    Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm.

    Tissue Specificity:
    Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus. 

    Similarity:
    Belongs to the GTP1/OBG family. 
    Contains 1 G (guanine nucleotide-binding) domain. 

    SWISS:
    Q9NTK5 

    Gene ID:
    29789

    Database links:

    Entrez Gene: 29789 Human

    Entrez Gene: 67059 Mouse

    Entrez Gene: 296488 Rat

    Omim: 611175 Human

    SwissProt: Q9NTK5 Human

    SwissProt: Q9CZ30 Mouse

    SwissProt: A0JPJ7 Rat

    Unigene: 157351 Human

    Unigene: 22661 Mouse

    Unigene: 5874 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 GTPBP9 antibody
    Sample: Raji Cell (Human) Lysate at 30 ug
    Primary: Anti-GTPBP9 (bs-9554R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 45kD
    Observed band size: 50kD

    GTPBP9 antibody
    Sample: Brain (Mouse) Lysate at 40 ug
    Primary: Anti-GTPBP9 (bs-9554R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 45kD
    Observed band size: 50kD

    GTPBP9 antibody
    Sample: 
    HepG2 Cell (Human) Lysate at 30 ug
    TT Cell (Human) Lysate at 30 ug
    Primary: Anti-GTPBP9 (bs-9554R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 45kD
    Observed band size: 50kD

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