DNase II antibody

DNase II antibody

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  • ¥1380 - 2200
  • 康朗生物
  • 中国/美国/德国
  • 2025年12月02日
  • WB=1:500-2000 ELISA=1:500-1000
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-23335R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      DNase II antibody

    • 抗体名

      脱氧核糖核酸酶2抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human DNase II:201-300/360

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    DNase II antibody
    中文名称 脱氧核糖核酸酶2抗体
    别    名 Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; DeoxyribonucleaseII; DNASE 2; DNASE 2A; DNase II alpha; DNase II lysosomal; DNASE2; DNASE2A; DNaseII; DNL 2; DNL; DNL2; DNS2A_HUMAN; Lysosomal DNase II; R31240 2; R31240_2.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  细胞凋亡  细胞周期蛋白  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 38kDa
    细胞定位 细胞浆 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DNase II:201-300/360 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

    Function:
    Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

    Subcellular Location:
    Lysosome. 

    Post-translational modifications:
    Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.

    Similarity:
    Belongs to the DNase II family.

    SWISS:
    O00115

    Gene ID:
    1777

    Database links:

    Entrez Gene: 1777 Human

    Omim: 126350 Human

    SwissProt: O00115 Human

    Unigene: 118243 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 DNase II antibody
    Sample: 
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti-DNase II (bs-23335R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 38 kD
    Observed band size: 53 kD

    DNase II antibody
    Sample: 
    Hela Cell Lysate at 30 ug
    Spleen (Mouse) Lysate at 40 ug
    Primary: Anti-DNase II (bs-23335R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 38 kD
    Observed band size: 53 kD

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