- ¥1580
- 康朗生物
- kl-6313R
- 中国/美国/德国
- 2025年12月31日
- ELISA=1:500-1000
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海康朗生物科技有限公司
- 库存：
大量
- 目录编号：
kl-6313R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
12个月
- 抗体英文名：
4 Hydroxynonenal antibody
- 抗体名：
4羟基壬烯酸抗体
- 宿主：
Rabbit
- 适应物种：
Human
- 免疫原：
KLH conjugated to 4 Hydroxynonenal:
- 亚型：
IgG
- 形态：
冻干粉或液体
- 应用范围：
ELISA=1:500-1000
- 浓度：
1mg/ml
- 保存条件：
-20 °C
- 规格：
100ul
| 中文名称 | 4羟基壬烯酸抗体 |
| 别 名 | 4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; (E)-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA. |
 |
Specific References (6) | bs-6313R has been referenced in 6 publications. [IF=3.97] Hong Duong, T. T., et al. "Pre‐Treatment With The Synthetic Antioxidant T‐Butyl Bisphenol Protects Cerebral Tissues From Experimental Ischemia Reperfusion Injury." Journal of Neurochemistry (2014). IHC-P ; Rat. PubMed:24766199 [IF=12.81] Haberman, Yael, et al. "Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature." The Journal of Clinical Investigation 124.124 (8) (2014): 0-0. IHC-P ; Human. PubMed:25003194 [IF=2.43] Zhang, Jing-Yao, et al. "Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice." World Journal of Gastroenterology 21.14 (2015): 4195-4209. IHC-P ; Mouse. PubMed:25892869 [IF=2.11] Kagaya, Kenta, et al. "Involvement of oxidative stress in increased peripheral nerve firing during spontaneous dysesthesia in a mouse model of ischemia-reperfusion." Neuroscience Letters (2016). other ; Mouse. PubMed:27555434 [IF=3.54] Sapkota, Arjun, et al. "Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation." PloS one 12.2 (2017): e0171479. IHC-F ; Mouse. PubMed:28178289 [IF=2.75] Guo, Chao, et al. "Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats." Journal of Ethnopharmacology (2012). IHC-P ; Rat. PubMed:23123262 |
| 规格价格 | 100ul/1580元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 产品类型 | 药物与化合物抗体 |
| 研究领域 | 细胞生物 免疫学 信号转导 细胞凋亡 药物及化合物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | 4-Hydroxynonenal |
| 产品应用 | ELISA=1:500-1000 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 0.20229kDa |
| 细胞定位 | 细胞浆 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated to 4 Hydroxynonenal: |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Reactive oxygen and nitrogen species (ROS/RNS) have taken center stage in the field of signal transduction. The enzymes responsible for the production of ROS and RNS have been unraveled and the participation of these species in numerous signaling pathways has been documented. The next step is to identify the targets of ROS and RNS and the mechanisms by which they alter their activity in the affected signaling pathway. This book provides relevant chemistry that can be applied across signaling systems and summarizes the current state of knowledge in the area of redox signaling. ROS and RNS have been implicated in inflammation, aging and cancer. Subcellular Location: Cytoplasmic SWISS: N/A CAS: 18286-49-2 Database links: CAS Number：18286-49-2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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文献和实验4-Hydroxy-2-Nonenal (4-HNE) Staining by Anti-HNE Antibody
, 4-hydroxynonenal (4-HNE), is the main product formed from omega 6-PUFA (5 ). 4-HNE, a highly toxic aldehyde product of lipid peroxidation (5 ), is a sensitive marker of oxidative damage and lipid peroxidation and can be evaluated by immunohistochemical staining
Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues
: dissolve 5 g of dry non‐fat milk in TBS (see recipe ) to a final volume of 100 ml Primary antibody for 4‐HNE, rabbit anti‐hydroxynonenal (HNE) (Alpha Diagnostics International cat. no. HNE
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