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- 详细信息
- 技术资料
- 供应商:
上海联迈生物工程有限公司
- 库存:
大量
- 目录编号:
LM-1192R
- 克隆性:
多克隆
- 抗原来源:
Rabbit
- 保质期:
1年
- 抗体英文名:
CD14
- 抗体名:
内毒素受体抗体
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 免疫原:
KLH conjugated synthetic peptide derived from mouse CD14:201-300/366
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
- 浓度:
1mg/ml
- 保存条件:
Store at -20 °C
- 规格:
50ul 100ul 200ul
CD14内毒素受体抗体
| 英文名称 | CD14 |
| 中文名称 | 内毒素受体抗体 |
| 别 名 | CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_MOUSE; Myeloid cell-specific leucine-rich glycoprotein. |
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Specific References (6) | bs-1192R has been referenced in 6 publications. [IF=3.48] Chen, Xiaoming, et al. " Sargassum fusiforme polysaccharide activates nuclear factor kappa-B (NF-κB) and induces cytokine production via Toll-like receptors." Carbohydrate Polymers (2014). other ; Rat. PubMed:24708959 [IF=7.81] Chen, Yen‐Ta, et al. "Melatonin Treatment further Improves Adipose‐Derived Mesenchymal Stem Cell Therapy for Acute Interstitial Cystitis in Rat." Journal of Pineal Research (2014). IHC-P ; Rat. PubMed:25132326 [IF=2.14] Nau, Christoph, et al. "Alteration of Masquelets induced membrane characteristics by different kinds of antibiotic enriched bone cement in a critical size defect model in the rats femur." Injury (2015). IHC-P ; Rat. PubMed:26652225 [IF=1.58] Sun, Bing, et al. "Tight junction proteins and gap junction proteins play important roles in high fat dietary atherosclerosis pathogenesis." Int J Clin Exp Pathol 9.8 (2016): 7969-7976. IHC-P ; Rat. PubMed:0 [IF=0.52] "Utomo, Pamudji, et al. ""Decreasing SDF1-CXCR4 Expression after Adipose-Derived Mesenchymal Stem Cells (ASCS) Treatment Combined with Freeze-Dried Amniotic Membrane Wrapping in Rat Sciatic Nerve Injury."" International Journal of ChemTech Research. " IF(ICC) ; Rat. PubMed:0 [IF=3.15] Sun, Cheuk-Kwan, et al. "Melatonin treatment enhances therapeutic effects of exosomes against acute liver ischemia-reperfusion injury." Am J Transl Res 9.4 (2017): 1543-1560. IHC-P ; Rat. PubMed:28469765 |
| 规格价格 | 50ul/780元 购买 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 50ul 100ul 200ul |
| 研究领域 | 细胞生物 免疫学 干细胞 细胞表面分子 细胞类型标志物 淋巴细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35/40kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse CD14:201-300/366 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] Function: Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. Subunit: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Similarity: Contains 11 LRR (leucine-rich) repeats. SWISS: P10810 Gene ID: 12475 Database links: Entrez Gene: 929 Human Entrez Gene: 12475 Mouse Omim: 158120 Human SwissProt: P08571 Human Unigene: 163867 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD14又称内毒素受体,属细胞表面糖蛋白家族成员之一。在机体免疫、防御系统引起的一系列反应中介导细胞识别LPS并引起细胞酪氨酸磷酸化、核因子NF-κB转位、触发细胞因子释放和氧自由基产生。CD14在细胞因子产生的调控方面起重要作用,因而对于CD14结构、功能及其临床意义的研究日益受到重视。 |
| 产品图片 | ![]() Protein: mouse lung lysate; Primary: rabbit Anti-CD14(bs-1192R) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000; Predicted band size: 40 kD Observed band size: 40 kD ![]() Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CD14 Polyclonal Antibody, Unconjugated(bs-1192R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
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CD14内毒素受体抗体
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