- ¥1380 - 2200
- LMAI Bio
- LM-11655R
- 进口/国产
- 2026年06月01日
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- Rabbit
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海联迈生物工程有限公司
- 库存：
大量
- 目录编号：
LM-11655R
- 克隆性：
多克隆
- 抗原来源：
Rabbit
- 保质期：
1年
- 抗体英文名：
Aggrecan
- 抗体名：
短蛋白聚糖抗体
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 免疫原：
KLH conjugated synthetic peptide derived from human Brevican/aggrecan (601-700aa):601-700/2415
- 亚型：
IgG
- 形态：
Lyophilized or Liquid
- 应用范围：
ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
- 浓度：
1mg/ml
- 保存条件：
Store at -20 °C
- 规格：
100ul 200ul
| 英文名称 | Aggrecan |
| 中文名称 | 短蛋白聚糖抗体 |
| 别 名 | Brevican; Aggrecan; BCAN; BEHAB; Brain enriched hyaluronan binding protein; Brevican core protein; Brevican core protein isoform 1; Brevican core protein isoform 2; Brevican proteoglycan; Chondroitin sulfate proteoglycan 7; Chondroitin sulfate proteoglycan BEHAB; CSPG7; MGC13038. |
| 规格价格 | 100ul/1380元 购买 200ul/2200元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 Alzheimer's |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 99kDa |
| 细胞定位 | 细胞膜 细胞外基质 分泌型蛋白 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Brevican/aggrecan (601-700aa):601-700/2415 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008] Function: Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C-terminal epitope EAMESE. Subunit: Interacts with TNR Subcellular Location: Isoform 1 is secreted, extracellular space, extracellular matrix; Isoform 2 is found on the membrane; Lipid-anchor, GPI-anchor. Post-translational modifications: Contains mostly chondroitin sulfate. O-glycosylated with a core 1 or possibly core 8 glycan. Similarity: Belongs to the aggrecan/versican proteoglycan family. Contains 1 C-type lectin domain. Contains 1 EGF-like domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Contains 2 Link domains. Contains 1 Sushi (CCP/SCR) domain. SWISS: P16112 Gene ID: 176 Database links: Entrez Gene: 176 Human Entrez Gene: 11595 Mouse Entrez Gene: 58968 Rat Entrez Gene: 403828 Dog Omim: 155760 Human SwissProt: Q28343 Dog SwissProt: P16112 Human SwissProt: Q61282 Mouse SwissProt: P07897 Rat Unigene: 2159 Human Unigene: 358571 Mouse Unigene: 54503 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |  Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Aggrecan) Polyclonal Antibody, Unconjugated (bs-11655R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.  Tissue/cell: bone of mouse embryo; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Aggrecan Polyclonal Antibody, Unconjugated(bs-11655R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验。但也有同一花中花丝长短不一的。如，十字花科植物的花中， 6枚雄蕊分两轮，外轮 2枚雄蕊的花丝较短，内轮 4枚的较长，称四强雄蕊；唇形科和玄参科植物的花中， 4枚雄蕊的花丝两长两短，称二强雄蕊。花丝通常彼此分离，但也有部分或全部连合在一起的，如棉花的花丝连合成一束，呈筒状，称单体雄蕊；蚕豆、刺槐的花丝合成两束，称二体雄蕊；蓖麻的花丝连合成多束，称多体雄蕊。 花药 花丝顶端膨大呈囊状的部分。常以药隔分成两个药室，每一药室具 1个或 2个花粉囊。花粉囊是产生花粉的地方。花药的壁由表
Metabolism 研究内容 FGF21 是一种由多种代谢应激在肝脏中诱导的激素，包括饥饿、蛋白质缺乏、单糖和乙醇等各种刺激。它作用于一个异聚细胞表面受体，由一个传统的 FGF 受体酪氨酸激酶（FGFR1c）与单通道跨膜蛋白 b-Klotho（KLB）复合物组成。 在人类中，乙醇是迄今为止所发现的、最有效的 FGF21 诱导剂。先前的研究表明，FGF21 能够抑制乙醇偏好，诱导个体自主饮水以防止脱水，并防止酒精诱导的肝损伤。 为了探究 FGF21 存在的重要性，本研究给野生型（WT）和 FGF
质浓度增高等因素又使肾单位髓袢上行支及肾远曲小管分泌T－H蛋白含量增加。T－H蛋白相对分子质量较大，易聚合成大分子聚合体，在高浓度电解质、酸性和浓缩尿时易聚集沉淀，在肾小管管腔内形成管型。 2.尿液浓缩和肾小管内环境酸化 这些存在于肾小管中的蛋白质由于浓缩，进一步提高了蛋白质的含量，而尿液酸化后又促进蛋白质凝固和沉淀，由溶胶状变为凝胶状并进一步固化，致使肾小管内尿液流速减慢，促使其在肾小管远端和集合管内形成管型。 3.有可提供交替
技术资料暂无技术资料 索取技术资料
