重组人肿瘤坏死因子α(N端His标签)现货

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人肿瘤坏死因子α(N端His标签)现货在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人肿瘤坏死因子α(N端His标签)现货
编号：JN0468
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human Tumor Necrosis Factor alpha
品牌：百奥莱博
产地：北京
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Gly57-Leu233在N端含有His标签。

TNF-alpha质量控制：＞95%(还原性SDS-PAGE)

TNF-alpha制剂：冻干品

TNF-alpha保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNF-alpha复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNF-alpha：
Tumor Necrosis Factor-α (TNF-α) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF-α while cells that express CD8 secrete little or no TNF-α. Synthesis of TNF-α can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumor activity of TNF-α has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF-α that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumor activity and reduced systemic toxicity in mice comp*(代"a")red with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF-α High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

重组人肿瘤坏死因子α(N端His标签)现货极具性价比，此外，我公司正火爆促销以下产品：

·重组人LIR-1
编号：JN1841
英文名称：Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly24-His458在C端含有His标签。

LIR-1质量控制：＞95%(还原性SDS-PAGE)

LIR-1制剂：冻干品

LIR-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LIR-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LIR-1：
The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.


重组人肿瘤坏死因子α(N端His标签)现货关键词：重组肿瘤坏死因子α,N端His标签,重组人肿瘤坏死因子α蛋白,JN0468


·重组人白介素IL-3(N端带His标签)
编号：JN0367
英文名称：Recombinant Human Interleukin-3
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备，目的基因编码的Ala20-Phe152在N端含有His标签

IL-3质量控制：＞95%(还原性SDS-PAGE)。

IL-3制剂：冻干品

IL-3保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-3复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-3：
Interleukin-3 (IL-3) is a potent growth promoting cytokine. IL-3 can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its biological function through binding to specific cell surface receptors. The amino acid sequences of this protein among different species share relatively low identity and its activity is highly species-specific. IL-3 has also been shown to possess neurotrophic activity, and is thought to be associated with neurologic disorders.


重组人肿瘤坏死因子α(N端His标签)现货关键词：重组肿瘤坏死因子α,N端His标签,重组人肿瘤坏死因子α蛋白,JN0468


·重组人SLAMF1(SLAM)(CD150)(信号淋巴细胞激活分子)
编号：JN1810
英文名称：Recombinant Human Signaling Lymphocytic Activation Molecule
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala21-Pro237在C端含有His标签。

SLAMF1/SLAM/CD150质量控制：＞95%(还原性SDS-PAGE)

SLAMF1/SLAM/CD150制剂：冻干品

SLAMF1/SLAM/CD150保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SLAMF1/SLAM/CD150复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SLAMF1/SLAM/CD150：
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销，满分期待您的垂询选购重组人肿瘤坏死因子α(N端His标签)现货。