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- 详细信息
- 技术资料
- 库存:
551
- 英文名:
Recombinant Human Apoptosis-Inducing Factor 1, Mitochondrial
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃以下可长期保存,室温
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人线粒体凋亡诱导因子1(AIFM1)现货价格,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人线粒体凋亡诱导因子1(AIFM1)现货价格
编号:JN0674
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human Apoptosis-Inducing Factor 1, Mitochondrial
品牌:百奥莱博
产地:北京
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Glu121-Asp613在N端含有His标签。
AIFM1质量控制:>95%(还原性SDS-PAGE)
AIFM1制剂:冻干品
AIFM1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
AIFM1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于AIFM1:
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces parthanatos i.e., caspase-independent fragmentation of chromosomal DNA. AIFM1 interacts with EIF3G, and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. It binds to DNA in a sequence-independent manner and plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
我公司的重组人线粒体凋亡诱导因子1(AIFM1)现货价格,性价比高,货期短,送货上门,欢迎您来电咨询购买,另外,我公司还生产供应销*(代"售")下列产品:
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HR0486 WST-1细胞增殖及细胞毒性检测试剂盒 WST-1 cell proliferation and cytotoxicity assay kit
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YT915 中性红染色液(活细胞染色用) Neutral Red Staining Solution(Living cell staining)
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YT011 DNA/RNA沉淀剂(Glycogen)(糖原) Glycogen for the precipitation of nucleic acid
重组人线粒体凋亡诱导因子1(AIFM1)现货价格关键词:重组人AIFM1,JN0674,重组人线粒体凋亡诱导因子1蛋白,重组线粒体凋亡诱导因子1
·重组人趋化因子CCL26(Eotaxin-3)
编号:JN0305
英文名称:Recombinant Human C-C Motif Chemokine 26
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Thr24-Leu94表达纯化而来。
CCL26/Eotaxin-3质量控制:>95%(还原性SDS-PAGE)。
CCL26/Eotaxin-3制剂:液体
CCL26/Eotaxin-3保存:
收到后请置于-20℃,可稳定保存6个月,避免反复冻融。
关于CCL26/Eotaxin-3:
Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
重组人线粒体凋亡诱导因子1(AIFM1)现货价格关键词:重组人AIFM1,JN0674,重组人线粒体凋亡诱导因子1蛋白,重组线粒体凋亡诱导因子1
·重组人趋化因子CCL16(HCC-4)
编号:JN0295
英文名称:Recombinant Human C-C Motif Chemokine 16
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Gln24-Gln120表达纯化而来。
CCL16/HCC-4质量控制:>95%(还原性SDS-PAGE)。
CCL16/HCC-4制剂:冻干品
CCL16/HCC-4保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
CCL16/HCC-4复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于CCL16/HCC-4:
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES, suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
我公司强烈推荐重组蛋白系列产品,热情期待您的咨询选购重组人线粒体凋亡诱导因子1(AIFM1)现货价格。
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