JN1421型重组小鼠LAG3(淋巴细胞活化基因3蛋白)供应

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

JN1421型重组小鼠LAG3(淋巴细胞活化基因3蛋白)供应的品牌：百奥莱博，是优质的重组蛋白产品，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠LAG3(淋巴细胞活化基因3蛋白)等重组蛋白产品请联*(代"系")我司咨询订购。

名称：JN1421型重组小鼠LAG3(淋巴细胞活化基因3蛋白)供应
编号：JN1421
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse Lymphocyte Activation Gene 3 Protein
品牌：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser23-Leu442在C端含有His标签。

LAG3质量控制：＞95%(还原性SDS-PAGE)

LAG3制剂：冻干品

LAG3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LAG3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LAG3 ：
Lymphocyte-activation gene 3 (LAG3), also known as CD223, is a type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4 and belongs to the immunoglobulin superfamily. The gene for LAG3 lies adjacent to the gene for CD4 on human chromosome 12p13.32 and shares approximately 20% identical to the CD4 gene. LAG3 is expressed on activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. LAG3 binds with high affinity to MHC class II molecules, and it interferes competitively with the binding of CD4 to MHC class II and thereby blocks the transduction of stimulatory signals mediated by this interaction. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and plays an important role in Treg suppressive function. LAG3 is the target of various drug development programs to develop new treatments for cancer and autoimmune disorders. The soluble form, sLAG-3, is being developed as a cancer drug.

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JN1421型重组小鼠LAG3(淋巴细胞活化基因3蛋白)供应关键词：JN1421,重组LAG3,重组小鼠淋巴细胞活化基因3蛋白,重组小鼠LAG3,重组小鼠LAG3蛋白


·重组人对羟*基丙*(代"酮")酸双氧化酶(4HPPD)
编号：JN0897
英文名称：Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Met393在N端含有His标签。

4HPPD质量控制：＞95%(还原性SDS-PAGE)

4HPPD制剂：液体

4HPPD保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于4HPPD：
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.


JN1421型重组小鼠LAG3(淋巴细胞活化基因3蛋白)供应关键词：JN1421,重组LAG3,重组小鼠淋巴细胞活化基因3蛋白,重组小鼠LAG3,重组小鼠LAG3蛋白


·重组人CEACAM7(癌胚抗原相关细胞粘附分子7)
编号：JN0767
英文名称：Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Thr36-Phe142在C端含有His标签。

CEACAM7质量控制：＞95%(还原性SDS-PAGE)

CEACAM7制剂：冻干品

CEACAM7保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CEACAM7复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CEACAM7：
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7) is a member of the immunoglobulin superfamily A and CEA family. CEACAM7 localizes to the cell membrane and contains one Ig-like C2-type domain and one Ig-like V-type domain. The expression of CEACAM7 is significantly decreased in rectal cancer. Differences in CEACAM7 expression levels between long-term survivors and those with recurrent disease introduce a potential tumor marker to define a subset of patients who benefit most from adjuvant therapy.

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