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Apelin Receptor antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-2430R
  • 中国/美国/德国
  • 2025年07月13日
  • WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test
  • Rabbit
  • Human, Mouse, Rat, Dog, Rabbit,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-2430R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      Apelin Receptor antibody

    • 抗体名

      血管紧张素II受体样蛋白1抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380 <Cytoplasmic>

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    Apelin Receptor antibody
    中文名称 血管紧张素II受体样蛋白1抗体
    别    名 APJ receptor; AGTR L1; AGTRL 1; AGTRL1; Angiotensin II receptor like 1; Angiotensin receptor like 1; Apelin receptor; APJ; B78; FLJ90771; G protein coupled receptor APJ; GPCR34; HG 11; HG11; MGC45246; MSR; msr/apj; Aplnr; Agtrl1; APLNR; FLJ96609; APJ_HUMAN.  
    产品细节图片1 Specific References  (2)     |     bs-2430R has been referenced in 2 publications.
    [IF=1.64] Izgüt-Uysal, V. N., et al. "The effect of apelin on the functions of peritoneal macrophages." Physiological research (2017).  IHC ;  Rat.  
    PubMed:28248533
    [IF=1.61] Ustunel, Ismail, et al. "The effects of water immersion and restraint stress on the expressions of apelin, apelin receptor (APJR) and apoptosis rate in the rat heart." Acta Histochemica (2014)  IHC-P ;  Rat.  
    PubMed:24411164
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 心血管  细胞生物  免疫学  G蛋白偶联受体  G蛋白信号  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=1μg/Test (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 42kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Apelin receptor:41-140/380 <Cytoplasmic>
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq

    Function:
    Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.

    Subcellular Location:
    Cell membrane.

    Tissue Specificity:
    Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.

    Similarity:
    Belongs to the G-protein coupled receptor 1 family.

    SWISS:
    P35414

    Gene ID:
    187

    Database links:

    Entrez Gene: 429337 Chicken

    Entrez Gene: 615435 Cow

    Entrez Gene: 187 Human

    Entrez Gene: 23796 Mouse

    Entrez Gene: 83518 Rat

    Omim: 600052 Human

    SwissProt: P35414 Human

    SwissProt: Q9WV08 Mouse

    SwissProt: Q9JHG3 Rat

    Unigene: 438311 Human

    Unigene: 29368 Mouse

    Unigene: 7965 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片2
    Sample: 
    Cerebrum(mouse) Lysate at 40 ug
    heart(mouse) Lysate at 40 ug
    Primary: Anti-Apelin receptor (bs-2430R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 42 kD
    Observed band size: 52 kD

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    图标文献和实验
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