5HT4 Receptor antibody

价格¥780 - 2200

品牌康朗生物
货号kl-2127R
产地中国/美国/德国
更新日期2025年07月08日

应用范围WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:200-800
宿主Rabbit
适应物种Human, Mouse, Rat, Chicken, Cow,

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供应商：
上海康朗生物科技有限公司
库存：
大量
目录编号：
kl-2127R
克隆性：
多克隆
抗原来源：
Rabbit
保质期：
12个月
抗体英文名：
5HT4 Receptor antibody
抗体名：
5-羟色胺受体4抗体
宿主：
Rabbit
适应物种：
Human, Mouse, Rat, Chicken, Cow,
免疫原：
KLH conjugated synthetic peptide derived from human 5-HTR4:21-120/388
亚型：
IgG
形态：
冻干粉或液体
应用范围：
WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:200-800
浓度：
1mg/ml
保存条件：
-20 °C
规格：
50ul 100ul 200ul

5HT4 Receptor antibody

中文名称	5-羟色胺受体4抗体
别名	5-HTR4 (5-hydroxytryptamine (serotonin) receptor 4a); Htr4a; 5-HT4; 5-HT4A; 5HT4; Htr45 HT 4; 5 HT4; 5 HT4R; 5 hydroxytryptamine 4 receptor; 5 hydroxytryptamine receptor 4; 5 hydroxytryptamine serotonin receptor 4; 5 hydroxytryptamine4 receptor; 5HT4; 5HT4R; Cardiac 5 HT4 receptor; HTR 4; HTR4; Serotonin 5 HT4 receptor; Serotonin receptor 4; 5HT4R_HUMAN.
规格价格	50ul/780元购买 100ul/1380元购买 200ul/2200元购买大包装/询价
说明书	50ul 100ul 200ul
研究领域	神经生物学信号转导通道蛋白细胞膜受体转运蛋白
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat, Chicken, Cow,
产品应用	WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:200-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	43kDa
细胞定位	细胞浆细胞膜
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human 5-HTR4:21-120/388
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Subunit: Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR. Subcellular Location: Cell membrane; Multi-pass membrane protein. Endosome. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. Tissue Specificity: soform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: Q13639 Gene ID: 3360 Database links: Entrez Gene: 3360 Human Entrez Gene: 15562 Mouse Entrez Gene: 25324 Rat GenBank: NP_000861.1 Human Omim: 602164 Human SwissProt: O70528 Guinea pig SwissProt: Q13639 Human SwissProt: P97288 Mouse SwissProt: Q29006 Pig SwissProt: Q62758 Rat Unigene: 483773 Human Unigene: 20440 Mouse Unigene: 10094 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti-5HT4 Receptor (bs- 2127R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD Sample: Large intestine (Mouse) Lysate at 40 ug Primary: Anti-5HT4 Receptor (bs-2127R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (5HT4 Receptor) Polyclonal Antibody, Unconjugated (bs-2127R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (5HT4 Receptor) Polyclonal Antibody, Unconjugated (bs-2127R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (5HT4 Receptor) Polyclonal Antibody, Unconjugated (bs-2127R) at 1:400 overnight at 4°C, followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) for 90 minutes, and DAPI for nuclei staining.