产品封面图

Caspase-3活化半胱胺酸蛋白酶蛋白-3抗体

收藏
  • ¥780 - 2200
  • LMAI Bio
  • LM-0081R
  • 进口/国产
  • 2025年07月11日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=2μg/Test IF=1:100-500 (石蜡切片需做抗原修复) 
  • Rabbit
  • Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-0081R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Caspase-3

    • 抗体名

      活化半胱胺酸蛋白酶蛋白-3抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 

    • 免疫原

      KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit:1-100/277 

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=2μg/Test IF=1:100-500 (石蜡切片需做抗原修复) 

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    Caspase-3活化半胱胺酸蛋白酶蛋白-3抗体
    英文名称 Caspase-3
    中文名称 活化半胱胺酸蛋白酶蛋白-3抗体
    别    名 Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.  
    产品细节图片1
    Specific References  (63)     |     bs-0081R has been referenced in 63 publications.
    [IF=5.47] Pan, Bo, et al. "c-Abl Tyrosine Kinase Mediates Neurotoxic Prion Peptide-Induced Neuronal Apoptosis via Regulating Mitochondrial Homeostasis." Molecular Neurobiology (2014): 1-15.  Rat.  
    PubMed:24510275
    [IF=2.75] Ye, Bengui, et al. "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." Journal of Ethnopharmacology (2014).  WB ;  Human.  
    PubMed:24583069
    [IF=2.69] Lin, Caiyu, et al. "Lithocarpus Polystachyus Rehd Leaf Aqueous Extract Inhibits Human Breast Cancer Growth In Vitro and In Vivo." Nutrition and Cancer (2014).  WB ;  Human.  
    PubMed:24660968
    [IF=3.17] Liu, Yang, et al. "Amelioration of Stroke-Induced Neurological Deficiency by Lyophilized Powder of Catapol and Puerarin." International Journal of Biological Sciences 10.4 (2014): 448-456.  WB ;  Mouse.  
    PubMed:24719562
    [IF=2.52] Yao, Kun, et al. "Knockdown of RLIP76 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to daunorubicin in U937 leukemia cells." Tumor Biology (2014): 1-9.  WB ;  Human.  
    PubMed:24839008
    [IF=2.15] Tang, Xi-Lan, et al. "The Cardioprotective Effect of Protocatechuic Acid on Myocardial Ischemia/Reperfusion Injury." Journal of Pharmacological Sciences 125.2 (2014): 176-183.  WB ;  Rat.  
    PubMed:24942213
    [IF=2.10] Zhang, Beiru, et al. "The Toxicity Mechanisms of Action of Aβ25–35 in Isolated Rat Cardiac Myocytes." Molecules 19.8 (2014): 12242-12257.  other ;  Rat.  
    PubMed:25123188
    [IF=3.79] Luo, Xiaoming, et al. "Antimetastasis and antitumor efficacy promoted by sequential release of vascular disrupting and chemotherapeutic agents from electrospun fibers." International Journal of Pharmaceutics (2014).  IHC-P ;  Mouse.  
    PubMed:25218185
    [IF=2.38] Gao, Hui, et al. "Hispidulin Potentiates the Antitumor Effect of Sunitinib Against Human Renal Cell Carcinoma in Laboratory Models." Cell Biochemistry and Biophysics: 1-8.  WB ;  Human.  
    PubMed:25260394
    [IF=2.38] Gao, Hui, et al. "shRNA-Mediated EMMPRIN Silencing Inhibits Human Leukemic Monocyte Lymphoma U937 Cell Proliferation and Increases Chemosensitivity to Adriamycin." Cell Biochemistry and Biophysics: 1-9.  WB ;  Human.  
    PubMed:25260396
    [IF=3.68] Xiao, Ke, et al. "The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats." Cell and Tissue Research (2014).  IHC-P ;  Rat.  
     
    [IF=3.53] Fang C, Zhang J, Qi D, Fan X, Luo J, et al. (2014) Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells. PLoS ONE 9(12): e115204.   WB ;  Human.  
    PubMed:25506932
    [IF=1.14] Wang, J., et al. "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." Brazilian Journal of Medical and Biological Research (2014): 000-000.  WB ;  Mouse.  
    PubMed:25517918
    [IF=4.20] Tian, A., et al. "Nanoscale TiO 2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells." International Journal of Nanomedicine10 (2015): 2377-2389.  Human.  
    PubMed:25848261
    [IF=3.84] Kubatka, Peter, et al. "Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer." European Journal of Nutrition(2015): 1-11.  IHC-P ;  Rat.  
    PubMed:25930965
    [IF=1.55] Jia, Jianping, et al. "A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms." Molecular Medicine Reports.  Human.  
    PubMed:26165988
    [IF=2.37] Liu, Jun-Song, et al. "β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation." World J Gastroenterol 21.34 (2015): 9945-9956.  WB ;  Human.  
    PubMed:26379399
    [IF=1.55] Song, Guijun, et al. "Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimers disease via mammalian target of rapamycin-dependent and-independent pathways." Molecular Medicine Reports.  WB ;  Human.  
    PubMed:not posted yet
    [IF=2.70] Lv, Runxiao, et al. "Neuroprotective effect of allicin in a rat model of acute spinal cord injury." Life Sciences (2015).  WB ;  Rat.  
    PubMed:26546416
    [IF=2.31] Dong, Liwei, et al. "Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1." OncoTargets and Therapy 8 (2015): 3649.  Human.  
    PubMed:26677335
    [IF=0.00] Wang, Yu, et al. "Tanshinone II A Relieves Adriamycin-induced Myocardial Injury in Rat Model." International Journal of Chemistry 8.1 (2016): 40.  WB ;  Rat.  
    PubMed:not posted yet
    [IF=3.82] Clark, Andrea J., et al. "WO3/Pt nanoparticles are NADPH oxidase biomimetics that mimic effector cells in vitro and in vivo." Nanotechnology27.6 (2015): 065101.  
    PubMed:26683660
    [IF=3.47] Kubatka, Peter, et al. "Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model." European Journal of Nutrition (2016): 1-14.  IHC-P ;  Rat.  
    PubMed:26907089
    [IF=1.06] Zhang, Xiaolin, and Hao Yu. "Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression (Supplement 2016)." Iranian Journal of Pharmaceutical Research (2016).  WB ;  Rat.  
    PubMed:27642320
    [IF=3.40] Gao, Hui, et al. "Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer."American Journal of Translational Research 8.2 (2016): 1115-1132  WB ;  Human.  
    PubMed:27158398
    [IF=2.53] Yoshinaga, Ayana, et al. "NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation." European Journal of Pharmacology (2016).  WB ;  Human.  
    PubMed:27105818
    [IF=0.00] Petty, Howard R. "NANOPARTICLE THERAPY IN CANCER." U.S. Patent No. 20,150,335,744. 26 Nov. 2015.  IF(ICC) ;  
    PubMed:1111
    [IF=2.90] Shan, Ming, and Ting-Jun Fan. "Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway." Toxicology in Vitro (2016).  ELISA ;  Human.  
    PubMed:27216471
    [IF=2.10] Hu, Hanhua, et al. "Drug-induced apoptosis of Echinococcus granulosus protoscoleces." Parasitology research 109.2 (2011): 453-459.  IHC-P ;  Others.  
    PubMed:21365454
    [IF=1.51] Sun, Y‐L., et al. "Relationship between apoptosis and proliferation in granulosa and theca cells of cystic follicles in sows." Reproduction in domestic animals 47.4 (2012): 601-608.  IHC-P ;  Pig.  
    PubMed:22023076
    [IF=1.55] Ding, Qing, et al. "8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells." Molecular medicine reports 12.4 (2015): 5100-5108.  WB ;  Human.  
    PubMed:26151347
    [IF=4.38] Ma, Xiangyi, et al. "DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors." Molecular pharmaceutics 10.1 (2013): 115-126.  IHC-P ;  Human.  
    PubMed:23198829
    [IF=1.55] Han, Ning, et al. "Agmatine protects Müller cells from high‑concentration glucose‑induced cell damage via N‑methyl‑D‑aspartic acid receptor inhibition." Molecular medicine reports 12.1 (2015): 1098-1106.  WB ;  Rat.  
    PubMed:25816073
    [IF=2.86] Liu, Yaping, et al. "Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice." International Journal of Molecular Sciences 17.1 (2016): 96.  WB ;  Mouse.  
    PubMed:26771609
    [IF=1.83] KASSAYOVÁ, MONIKA, et al. "Anticancer and Immunomodulatory Effects of Lactobacillus plantarum LS/07, Inulin and Melatonin in NMU-induced Rat Model of Breast Cancer." Anticancer Research 36.6 (2016): 2719-2728.  IHC-P ;  Rat.  
    PubMed:27272781
    [IF=1.72] Zhao, Jun, et al. "The cytotoxic and pro-apoptotic effects of phenylephrine on corneal stromal cells via a mitochondrion-dependent pathway both in vitro and in vivo." Experimental and Toxicologic Pathology (2016).  ELISA ;  Human.  
    PubMed:27344612
    [IF=6.01] Chen, Zhoujiang, et al. "Tunable conjugation densities of camptothecin on hyaluronic acid for tumor targeting and reduction-triggered release." Acta Biomaterialia (2016).  IHC-P ;  Mouse.  
    PubMed:27424081
    [IF=3.92] Wei, Gang, et al. "β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice." Journal of Alzheimer's Disease 33.3 (2013): 863-880.  IF(ICC) ;  Mouse.  
    PubMed:23064259
    [IF=1.48] Liu, Yong‑Chao, et al. "RNAi-mediated gene silencing of vascular endothelial growth factor C suppresses growth and induces apoptosis in mouse breast cancer in vitro and in vivo." Oncology Letters. (2016)  WB ;  Mouse.  
    PubMed:27666771
    [IF=2.13] Cetintas, Vildan Bozok, et al. "Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells." Medicine 95.43 (2016): e5150.  IF(ICC) ;  Mouse.  
    PubMed:27787370
    [IF=3.85] Wang, Yandi, et al. "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." Toxicology and Applied Pharmacology (2016).  IHC-P ;  Sheep.  
    PubMed:27815134
    [IF=5.23] Zhao, Yong, et al. "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." Scientific Reports 6 (2016): 37884.  WB ;  Pig.  
    PubMed:27883089
    [IF=1.64] Kosutova, P., et al. "Intravenous dexamethasone attenuated inflammation and influenced apoptosis of lung cells in an experimental model of acute lung injury." Physiological research 65.Supplementum 5 (2016): S663.  IHC-P ;  Rabbit.  
    PubMed:28006948
    [IF=2.38] Abdel-Hamid, Nagwa I., Mona F. El-Azab, and Yasser M. Moustafa. "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." Naunyn-Schmiedeberg's Archives of Pharmacology (2017): 1-17.  IHC-P ;  Rat.  
    PubMed:28070612
    [IF=1.55] Yang, Jinjiang, Ying Lu, and Ai Guo. "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." Molecular Medicine Reports 14.5 (2016): 4075-4082.  WB ;  Rat.  
    PubMed:27665780
    [IF=0.87] Ochigbo, Grace Onyeche, et al. "Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis." Journal of Ayurveda and Integrative Medicine (2017).  Rat.  
    PubMed:28256303
    [IF=1.56] Qu, Zhongyuan, et al. "Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells." Molecular medicine reports 13.2 (2016): 1336-1344.  WB ;  Human.  
    PubMed:26677104
    [IF=2.33] Yang, Juan, Guiyuan Li, and Keqiang Zhang. "Pro-survival effects by NF-κB, Akt and ERK (1/2) and anti-apoptosis actions by Six1 disrupt apoptotic functions of TRAIL-Dr4/5 pathway in ovarian cancer." Biomedicine & Pharmacotherapy 84 (2016): 1078-1087.  WB ;  Human.  
    PubMed:27780136
    [IF=3.23] Wang, Yu, et al. "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." PloS one 12.4 (2017): e0173469.  WB ;  Rat.  
    PubMed:28399139
    [IF=4.94] Kubatka, Peter, et al. "Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma." Journal of Cellular and Molecular Medicine (2017).  IHC-P ;  Rat.  
    PubMed:28524540
    [IF=3.13] Zhang, Wen-feng, et al. "Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo." Phytomedicine (2017).  WB ;  Human.  
    PubMed:0
    [IF=9.91] Li, Ting, et al. "Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke." Brain (2013): awt287.  Mouse.  
    PubMed:24154617
    [IF=7.60] Teng, I., et al. "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." Biomaterials (2013).  WB ;  Mouse.  

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    相关实验
    • 跑个漂亮的 Caspase-3 结果图,真的那么难吗?

      Caspase-3(CPP-32,Apoptain,Yama,SCA-1),半胱天冬酶家族成员之一,是凋亡的关键执行者,对许多关键的蛋白起着部分或全部的裂解作用,如核酶多聚(ADP-ribose)聚合酶(PARP)[1] 及众多细胞骨架相关的蛋白、激酶以及 Bcl-2 家族中凋亡相关的蛋白等[2] 。Caspase-3 在肺、脾脏、心脏、肝脏、肾脏等中广泛表达,在大脑和骨骼肌中表达量稍低,在睾丸中表达量最低。同时在许多细胞系中都有发现 caspase-3 的表达,其中免疫相关的细胞中表达量最高

    • JCI 重磅:王福生院士团队发现 HIV 感染者体内 T 细胞损耗元凶!

      -1 和 caspase-3 激活形式的抗体进行胞内染色。 随后,研究人员纳入了 80 例 Viremic HIV-1-Infected 患者(VIR),41 例进行了成功的抗逆转录病毒治疗的患者(ART),7 例病毒得到严格控制的患者(EC)以及 19 例健康对照。纳入人群的详细临床特征如下表所示。 图片来源:JCI 首先,研究人员比较了四组人群中 CD4+ T 细胞表达活化的 caspase-1 和 caspase-3 的情况,结果发现,无论是 caspase-1,还是 caspase-3,其活化比例均在 VIR

    • 【求助】caspase-3抗体与激活型caspase-3抗体

      环佩从容 要做下一步实验啦,这两个抗体选哪个呀,目前研究有没有区分哪一个更好点啊 ronaldo_zj 楼主您好。 1. 楼主需要知道Pro caspase-3以及Cleaved caspase-3的功能以及检测手段,不是说哪个好那个不好的问题,而是根据你的课题需要检测何种片段的问题。请楼主先具体查阅关于caspase活化的文献后再定好实验计划; 2. 目前多数研究均认为Cleaved

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    询价
    上海梵态生物科技有限公司
    2025年07月16日询价
    ¥1380
    上海彩佑实业有限公司
    2025年07月14日询价
    询价
    上海古朵生物科技有限公司
    2025年07月10日询价
    询价
    上海钰博生物科技有限公司
    2025年07月11日询价
    询价
    上海远慕生物科技有限公司
    2025年07月12日询价
    Caspase-3活化半胱胺酸蛋白酶蛋白-3抗体
    ¥780 - 2200