TM2D1 antibody

TM2D1 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-19942R
  • 中国/美国/德国
  • 2025年12月08日
  • ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-19942R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      TM2D1 antibody

    • 抗体名

      β淀粉样蛋白结合蛋白抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human TM2D1:38-100/207 

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    TM2D1 antibody
    中文名称 β淀粉样蛋白结合蛋白抗体
    别    名 BBP; Beta amyloid binding protein; hBBP; TM2 domain containing 1; TM2 domain containing protein 1; TM2D1.  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  神经生物学  信号转导  细胞凋亡  Alzheimer's  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
    产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 19kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human TM2D1:38-100/207 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. [provided by RefSeq, Dec 2008]

    Function:
    May participate in beta-amyloid-induced apoptosis via its interaction with beta-APP42.

    Subunit:
    Interacts with beta-APP42 (beta-amyloid protein 42) peptide of APP.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Widely expressed.

    Post-translational modifications:
    N-glycosylated.

    Similarity:
    Belongs to the TM2 family.

    SWISS:
    Q9BX74

    Gene ID:
    83941

    Database links:

    Entrez Gene: 83941 Human

    Entrez Gene: 94043 Mouse

    Entrez Gene: 362545 Rat

    Omim: 610080 Human

    SwissProt: Q9BX74 Human

    SwissProt: Q99MB3 Mouse

    Unigene: 656790 Human

    Unigene: 331719 Mouse

    Unigene: 198278 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

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